Table 2 Association of LEPR rs1137101 with obesity measures and metabolic parameters in the overall study group and overweight or obese subjects (BMI ≥ 25 kgm−2)

From: Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans

 Overall study groupOverweight or obese (BMI ≥ 25 kgm−2)
AA n = 107AG n = 272GG n = 151pp*AA n = 53AG n = 141GG n = 70pp*
BMI (kgm−2)24.4 ± 4.125.1 ± 4.125.2 ± 4.50.280.3127.6 ± 2.628.2 ± 2.829.0 ± 3.30.030.04
WC(cm)88.0 ± 10.789.4 ± 10.689.8 ± 11.30.410.3695.2 ± 7.495.9 ± 7.798.4 ± 8.40.040.02
WHR0.92 ± 0.070.92 ± 0.070.92 ± 0.060.780.940.94 ± 0.070.94 ± 0.070.94 ± 0.060.890.94
FBS (mmol/l)5.3 ± 2.55.6 ± 3.95.2 ± 2.00.450.655.2 ± 1.95.6 ± 2.55.4 ± 2.20.530.52
TC (mmol/l)5.5 ± 0.95.8 ± 1.25.8 ± 2.10.410.455.4 ± 1.05.8 ± 1.35.9 ± 2.70.180.19
LDL-C (mmol/l)3.5 ± 0.93.8 ± 1.74.0 ± 3.30.190.193.4 ± 1.03.8 ± 2.24.5 ± 4.70.080.09
HDL-C (mmol/l)1.3 ± 0.31.5 ± 1.51.4 ± 0.30.350.521.3 ± 0.31.4 ± 0.31.4 ± 0.30.160.38
TGL (mmol/l)3.3 ± 1.63.4 ± 1.73.4 ± 2.60.490.563.3 ± 1.43.6 ± 1.83.8 ± 3.30.620.45
  1. Data shown as mean ± SD; FBS, HDL-C and TGL log transformed for analysis
  2. BMI body mass index, WC waist circumference, WHR waist-to-hip ratio, FBS fasting blood sugar, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TGL triglycerides
  3. p unadjusted; p* adjusted for age and gender