Burns are a prevalent and burdensome critical care problem. The priorities of specialized facilities focus on stabilizing the patient, preventing infection, and optimizing functional recovery. Research on burns has generated sustained interest over the past few decades, and several important advancements have resulted in more effective patient stabilization and decreased mortality, especially among young patients and those with burns of intermediate extent. However, for the intensivist, challenges often exist that complicate patient support and stabilization. Furthermore, burn wounds are complex and can present unique difficulties that require late intervention or life-long rehabilitation. In addition to improvements in patient stabilization and care, research in burn wound care has yielded advancements that will continue to improve functional recovery. This article reviews recent advancements in the care of burn patients with a focus on the pathophysiology and treatment of burn wounds.
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The authors would like to thank the staff of the Clinical Trials task area at the US Army Institute of Surgical Research for administrative support. The authors would also like to thank Dr Harold Klemcke for critical review of this manuscript. This work was supported in part by an appointment (MPR) to the Postgraduate Research Participation Program and an appointment (LCC) to the Knowledge Preservation Program at the US Army Institute of Surgical Research administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the US Department of Energy and US Army Medical Research and Materiel Command.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.
The authors declare that they have no competing interests.
MPR and KKC outlined the paper. MPR wrote all drafts of the manuscript, with primary editing and revision support from LCC. All authors contributed information for the manuscript, participated in its revision, and approved the final version for publication.
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Rowan, M.P., Cancio, L.C., Elster, E.A. et al. Burn wound healing and treatment: review and advancements. Crit Care 19, 243 (2015). https://doi.org/10.1186/s13054-015-0961-2