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Table 1 Pathway-log2FC of KD BHLHE40 SAL vs. Control SAL

From: The clock gene BHLHE40 and atypical CCNG2 control androgen-induced cellular senescence as a novel tumor suppressive pathway in prostate cancer

 

p-value

Regulation of expression of SLITs and ROBOs

4.78E-28

Signaling by ROBO receptors

3.84E-27

RHOA GTPase cycle

1.67E-18

VEGFA-VEGFR2 Pathway

4.78E-05

Signaling by WNT

4.87E-05

p53-Dependent G1 DNA Damage Response

0.000218

DNA Repair

3.89E-19

Cellular Senescence

2.93E-05

Signaling by NOTCH1 in Cancer

0.000195

Oncogene Induced Senescence

3.95E-06