Retraction Note: J Exp Clin Cancer Res 37, 17 (2018)
The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding highly similar images in the figures. Specifically:
-
Figure 1b shRNA CTR MHCC-97L image appears highly similar to Fig. 6g shRNA CTR miR-185 inhibitor.
-
Figure 3a MHCC-97L ITGB5 blot image appears highly similar to Fig. 3n WB: anti-Ub (stretched vertically).
-
Figure 4h shRNA ITGB5 CTR image appears highly similar to Fig. 6g shRNA ITGB5 miR-185 inhibitor.
-
Figure 4j shRNA ITGB5 and Fig. 6i shRNA CRT miR-185 inhibitor images appear to overlap.
-
Figure 6j shRNA β-catenin CTR and shRNA ITGB5 miR-185 inhibitor images appear to overlap.
The authors have stated that the images were misused, and provided the raw data for validation. However, due to the number and severity of concerns, the Editor-in-Chief no longer has confidence in the presented data.
Zhikun Lin has stated on behalf of all co-authors they do not agree to this retraction.
Author information
Authors and Affiliations
Corresponding authors
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
The online version of the original article can be found at https://doi.org/10.1186/s13046-018-0691-9
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Lin, Z., He, R., Luo, H. et al. Retraction Note: Integrin-β5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating β-catenin stability. J Exp Clin Cancer Res 42, 176 (2023). https://doi.org/10.1186/s13046-023-02762-6
Published:
DOI: https://doi.org/10.1186/s13046-023-02762-6