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Table 1 Differences in the levels of SUVR of [11C]NE40 and [11C] (R)PK11195

From: Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study

Age

[11C]NE40

[11C] (R)PK11195

Cerebral cortex

Hippocampus

Cerebral cortex

Hippocampus

 5 weeks

1.18 ± 0.37

1.07 ± 0.23

0.85 ± 0.21

0.86 ± 0.21

 15 weeks

1.41 ± 0.43*a

1.24 ± 0.38b

0.89 ± 0.16

0.94 ± 0.19

  1. *p < 0.05 vs cerebral cortex [11C](R)PK11195 value (Tukey’s multiple comparisons test)
  2. Tendency for significant difference (ap = 0.08, bp = 0.10) vs 5-week-old mice data in [11C]NE40 measurement
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