Fig. 4
From: DNMT1 facilitates growth of breast cancer by inducing MEG3 hyper-methylation
MEG3 inversely modulates miR-494-3p to promote OTUD4 expression and inhibits growth of breast cancer cells. A MEG3, miR-494-3p and OTUD4 expression in oe-NC + sh-NC, oe-MEG3 + sh-NC, oe-MEG3 + sh-OTUD4-1 and oe-MEG3 + sh-OTUD4-2 groups was detected by qRT-PCR and B OTUD4 protein expression was tested by western blot; C cell proliferation, D migration and E invasion were measured. *p < 0.05