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Table 1 Main effects and G × E interaction effects a

From: Identification of interactions using model-based multifactor dimensionality reduction

Trait Env. Factor SNP Chr. Position Gene p Value
HS rs145441374 13 53 420 325 PCDH8 8.135 × 10−5
rs1639 19 45 772 798 DMPK 1.883 × 10−5
rs1991818 19 51 485 013 KLK7 4.645 × 10−5
DBP rs2073371 21 32 493 204 TIAM1 7.396 × 10−5
SBP Age rs859400 1 175 375 334 TNR 0.0415
  1. a Results of model-based multifactor dimensionality reduction (MB-MDR) analyses for main effects of single-nucleotide polymorphisms (SNPs) and with sex and age (young, middle, old) as environmental factors (Env. Factor). Traits are hypertension status (HS), systolic blood pressure (SBP) and diastolic blood pressure (DBP). Interactions with p value <0.05 are shown with chromosome (Chr.), position and associated gene