Healthcare workers are at a higher risk of COVID-19 infection during care encounters compared to the general population. Personal Protective Equipment (PPE) have been shown to protect COVID-19 among healthcare workers, however, Kenya has faced PPE shortages that can adequately protect all healthcare workers. We, therefore, examined the health and economic consequences of investing in PPE for healthcare workers in Kenya.
We conducted a cost-effectiveness and return on investment (ROI) analysis using a decision-analytic model following the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) guidelines. We examined two outcomes: 1) the incremental cost per healthcare worker death averted, and 2) the incremental cost per healthcare worker COVID-19 case averted. We performed a multivariate sensitivity analysis using 10,000 Monte Carlo simulations.
Kenya would need to invest $3.12 million (95% CI: 2.65–3.59) to adequately protect healthcare workers against COVID-19. This investment would avert 416 (IQR: 330–517) and 30,041 (IQR: 7243 – 102,480) healthcare worker deaths and COVID-19 cases respectively. Additionally, such an investment would result in a healthcare system ROI of $170.64 million (IQR: 138–209) – equivalent to an 11.04 times return.
Despite other nationwide COVID-19 prevention measures such as social distancing, over 70% of healthcare workers will still be infected if the availability of PPE remains scarce. As part of the COVID-19 response strategy, the government should consider adequate investment in PPE for all healthcare workers in the country as it provides a large return on investment and it is value for money.
On March 11, 2020, the World Health Organization (WHO) declared coronavirus 2019 (COVID-19) a global pandemic. The WHO estimates that 10% of the global COVID-19 clinically diagnosed cases are among health workers with over 10,000 of the infected health workers coming from 40 African countries . Health care workers have been reported to have 11.7 times the risk of testing positive for COVID-19 compared to the general community . This increased risk of infection has been primarily attributed to a lack of adequate personal protective equipment (PPE) [3, 4].
Although existing evidence indicates that the type of PPE may determine the level of protection against COVID-19 infection among healthcare workers , there is a consensus for the consistent use of PPEs (a surgical mask, gloves, eye protection and a gown) when providing care for COVID-19 patients [2, 6]. Providing PPE to healthcare workers is, therefore, a critical component of the response to the COVID-19 pandemic [7, 8].
Countries are experiencing PPE shortages for frontline health care workers. PPE availability is affected by increased demand, global supply chain disruptions resulting from interventions to control the pandemic , challenges with ensuring rational use, ensuring supplies are preserved for areas with the greatest need, and lack of accountability in delivering PPE supplies to the frontline. This is despite the growth in local manufacturing of PPE in many countries and gradual improvements in international supply chains .
Ensuring healthcare workers are protected from COVID-19 infection is paramount especially in those countries with low healthcare worker numbers in absolute and relative terms . These same countries will experience greater strain on their ability to manage cases of COVID-19.
Kenya is a lower-middle-income country with 13.8 health care workers per 10,000 population in 2016. There is a steady pipeline of human resources for health development mainly from non-university tertiary level institutions [12, 13]. The workers are employed in both public and private sectors with dual practice common . Public sector employment is mainly through county governments who are the main providers of public health services . Private sector employment is through not-for-profit and for-profit organizations and sole proprietorships . Healthcare workers are inequitably distributed with urban areas attracting and retaining more. There are challenges with the effective management of public sector workers contributing to repeated episodes of industrial action in recent years .
Kenya reported 3068 infections and 32 mortalities among healthcare workers as of 11th January 2021 . This represents 3.1% of total infections as of this date. Anecdotal evidence identifies the availability of PPE as a key contributor to these infections. Concerns about the availability of PPE in Kenya have led to industrial unrest among healthcare workers . The impacts of continued infection of healthcare workers are likely to be severe but are yet unknown. This paper seeks to quantify the costs and cost-effectiveness of availing adequate PPE to healthcare workers in Kenya and the resulting return on investment.
For this analysis, we adopted an approach described elsewhere  to generate country-specific estimates for Kenya. In summary, we developed a decision-analytic model (Fig. 1) to compare the costs and effects of two PPE use scenarios in Kenya following the Consolidated health economic evaluation reporting standards (CHEERS) guidelines .
We compared a scenario where adequate/full PPE utilisation reduces healthcare worker infection and mortality to a scenario where healthcare workers had an inadequate supply of PPE thus higher rates of infection and mortality. PPE was considered adequate if healthcare workers had access to gloves, gown, surgical masks, and face shields, otherwise, a lack of either of these was considered as inadequate supply of PPE. Two outcomes were examined: 1) the incremental cost per healthcare worker death averted and 2) the incremental cost per healthcare worker case averted.
We then performed a Return on Investment (ROI) analysis that compared the health system economic benefits from having all healthcare workers protected against COVID-19 infection to the investment required to afford the PPE.
Several data sources and approaches were adopted for this analysis. Our definition of healthcare workers includes those recorded as nurses, clinical officers, doctors and lab technologists in the Statistical Abstract .
First, we utilised the WHO COVID-19 Essential Supplies Forecasting Tool (ESFT) to estimate the costs and required resources . The projections represent a 30-week period starting March 2021 following the WHO guideline on PPE requirements .
Second, healthcare worker labour costs were abstracted from a salary survey in four counties in Kenya (data not yet published) whereas costs for utilization of COVID-19 services were adopted from a cross-sectional study in Kenya . Costs are presented in 2020 US dollars from a health system perspective. We used an exchange rate of 1 USD = KES 108.43 to convert the costs into 2020 US dollars. In the model these costs also accounted for the healthcare worker lost productivity resulting from an early death or hospitalization. Our study also included training costs (unlike in the global study – Risko et al., ) for the different cadres of healthcare workers in Kenya. Training costs included the tuition fees, living expense and costs for obtaining required licences to practice for the different cadres of healthcare workers included in this study [25, 26]. Costs/benefits were not discounted as the investment would be required to be done over a short period of less than 1 year. Healthcare worker premature death was estimated to result in the loss of 16 years of working life (calculated as the difference between retirement age – 60 years – and the average age of a healthcare worker – 44 years . In Kenya, healthcare workers are comprised of doctors, nurses, clinical officers, technicians and ancillary staff. Table 1 summarises the main parameter values, their ranges, distribution and sources.
Third, we performed probabilistic sensitivity (PSA) analyses to examine how a simultaneous change in all random parameters affected the ICER using 10,000 simulations . Beta distributions were used for sampling within the 95% confidence interval of probability variables, gamma distributions for cost variables and lognormal distribution for the remaining parameters. We present these simulation results as cost-effectiveness planes and cost-effectiveness acceptability curves.
At baseline, the model predicts that across Kenya there will be 32,299 healthcare worker cases and 446 deaths if PPE supply is limited. However, with adequate PPE, only 2189 healthcare worker cases and 30 deaths would be recorded. An extra investment of USD 1.56 million will be required to achieve the reduced number of healthcare worker cases and deaths under the adequate PPE scenario. With this investment, an average of 30,041 healthcare worker cases and 416 healthcare worker deaths will be averted. Overall, a ROI from productivity gains is estimated to be USD 170.64 million, translating into a 11.04 times ROI. Table 2 summarizes the findings from this analysis.
Figure 2 shows the cost-effectiveness plane scatter plot for the number of healthcare worker deaths averted in Kenya. All simulated observations indicate that a higher number of healthcare worker deaths are averted when healthcare workers are provided with adequate PPE compared to when the availability of PPE for healthcare workers is limited. However, this would require an additional investment. Figure 3 shows the cost-effectiveness acceptability curve indicating the probability that the scenario with adequate PPE would be cost-effective at averting a healthcare worker death compared to the current scenario where healthcare workers have inadequate PPE over a range of investment values (willingness to pay thresholds). There is a 50, and 75% chance that relative to providing inadequate PPE, investing in adequate PPE would be value for money (cost-effective) if the government or donor would be willing to invest USD 3700, and USD 4800 per averted COVID-19 HCW death.
Figure 4 shows the cost-effectiveness plane scatter plot for the number of healthcare worker COVID-19 cases averted in Kenya whereas Fig. 5 shows the cost-effectiveness acceptability curve indicating the probability that the scenario with adequate PPE would be cost-effective at averting a healthcare worker COVID-19 case relative to when healthcare workers have inadequate PPE. Relative to inadequate PPE for healthcare workers, investing in adequate PPE would be 25, 50, and 75% cost-effective if the government or donor is willing to pay USD 210, USD 417 and USD 517 per healthcare worker COVID-19 case averted.
This study examined the cost-effectiveness and return on investment (ROI) of protecting healthcare workers in Kenya with personal protective equipment (PPE) during the COVID-19 pandemic using data from Kenya models alongside the WHO ESFT estimates. We found that providing adequate PPE results in 30,041 cases and 416 deaths averted, however, an investment of USD 1.55 million would be required. Such an investment results in a healthcare system gains of USD 170.64 million, equivalent to an 11.04 times ROI.
The higher number of healthcare worker cases and deaths averted is consistent with evidence suggesting that adequate PPE confer some protection against COVID-19 among healthcare workers [2, 5, 37, 38]. Additionally, our findings are similar to those reported by Risko et al. .
With the increasing number of COVID-19 cases and healthcare workers contributing over 7% of all cases, there is a need for further investment into PPE. However, this investment should be tied to the enforcement of strict PPE guidelines in the country. Evidence from studies in China showed a decline in the number of cases acquired in the healthcare setting from 41 to 3.8% after enforcing compliance to PPE use [39, 40].
Findings from this study should be interpreted with consideration to the following limitations. First, we omitted several cadres of healthcare workers from the analysis, including community health workers (CHW). Protecting CHW is critical to supporting home-based isolation and care, and other aspects of the pandemic response . Including CHW could have resulted in an even better ROI. Second, not all healthcare workers utilize all PPE daily and our findings may overestimate the investment required to adequately protect all healthcare workers. However, we considered this overestimate as the use of all PPE would reduce the risk of infection among healthcare workers during care encounters. Furthermore, existing evidence supports a zero to low healthcare worker infection rates in countries with stringent PPE compliance . Third, there is a chance that the COVID-19 related mortality in Kenya may be higher than predicted in the model we used as a result of a likely underreporting of COVID-19 deaths in Kenya. If indeed the mortality rate is higher than predicted, then more healthcare worker deaths could be averted for the same investment.
This analysis provides evidence to inform policy in Kenya and other LMIC of the value of investing in PPE for healthcare workers. Specifically, investing in adequate PPE for protecting all healthcare workers in Kenya has over 10-fold return and would prevent over 70% infection among HCW. We recommend urgent investment into PPEs for health workers but also adherence to the appropriate use of the PPEs.
Consolidated Health Economic Evaluation Reporting Standards
Community Health Worker
Essential Supplies Forecasting Tool
Gross Domestic Product
Health Care Workers
Incremental Cost Effectiveness Ratio
Low- and Middle-Income Countries
Personal Protective Equipment
Probabilistic Sensitivity Analysis
Return on Investment
United States Dollars
World Health Organization
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JK is supported by a Wellcome Trust Masters Fellowship grant number (212347). VW is supported by a grant from the International Decision Support Initiative (iDSI). The funders and the World Bank had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The views expressed in the paper are for the authors and not for the organizations they represent. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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Kazungu, J., Munge, K., Werner, K. et al. Examining the cost-effectiveness of personal protective equipment for formal healthcare workers in Kenya during the COVID-19 pandemic. BMC Health Serv Res 21, 992 (2021). https://doi.org/10.1186/s12913-021-07015-w
- Return on investment
- Healthcare workers
- Front-line workers