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Table 2 Univariate analysis of factors influencing post-treatment recurrence in lung adenocarcinoma

From: Construction and validation of a recurrence prediction model for lung adenocarcinoma after treatment integrating radiomics features and clinical indicators

Variables

Recurrence group (n = 74)

Non-Recurrence group (n = 171)

t/χ²

P

Age (years)

64.85 ± 7.90

63.21 ± 7.40

1.560

0.12

Gender (Male/Female)

39/35

99/72

0.566

0.451

Smoking history (years)

22.84 ± 10.55

16.24 ± 10.01

4.661

0.001

mMRC (score)

1.91 ± 0.93

1.88 ± 0.93

0.232

0.817

VAS (0–10 points)

4.26 ± 1.75

4.24 ± 1.72

0.083

0.934

Pathological type (Adenocarcinoma/Adenosquamous carcinoma)

68/6

162/9

0.300

0.573

TNM stage (I-II/III-IV)

35/39

112/59

7.128

0.007

CEA(ng/mL)

6.84 ± 2.32

5.50 ± 2.01

4.569

0.001

CYFRA21-1(ng/mL)

3.80 ± 1.40

3.60 ± 1.01

1.259

0.209

Maximum tumor diameter (mm)

29.44 ± 8.58

29.21 ± 8.32

0.197

0.844

Tumor volume (mm³)

1288.67 ± 432.55

1286.67 ± 432.50

0.033

0.973

Long-axis to short-axis ratio

0.48 ± 0.11

0.69 ± 0.20

8.488

0.001

Sphericity

0.73 ± 0.10

0.71 ± 0.11

1.342

0.181

Radiomics energy value

125.87 ± 35.48

125.43 ± 35.32

0.089

0.929

Gray-level co-occurrence matrix contrast

23.66 ± 8.78

23.26 ± 8.71

0.329

0.742

Gray-level run-length matrix

long-run emphasis

0.33 ± 0.14

0.30 ± 0.11

1.780

0.073

Gray-level standard deviation

18.86 ± 5.38

18.56 ± 5.20

0.410

0.681

Radiomics entropy

4.53 ± 0.92

4.01 ± 0.77

4.569

0.001

Mean gray-level value (CT value, HU)

45.77 ± 10.34

45.57 ± 10.01

0.142

0.887