Table 2 Univariate analysis of factors influencing post-treatment recurrence in lung adenocarcinoma
Variables | Recurrence group (n = 74) | Non-Recurrence group (n = 171) | t/χ² | P |
|---|---|---|---|---|
Age (years) | 64.85 ± 7.90 | 63.21 ± 7.40 | 1.560 | 0.12 |
Gender (Male/Female) | 39/35 | 99/72 | 0.566 | 0.451 |
Smoking history (years) | 22.84 ± 10.55 | 16.24 ± 10.01 | 4.661 | 0.001 |
mMRC (score) | 1.91 ± 0.93 | 1.88 ± 0.93 | 0.232 | 0.817 |
VAS (0–10 points) | 4.26 ± 1.75 | 4.24 ± 1.72 | 0.083 | 0.934 |
Pathological type (Adenocarcinoma/Adenosquamous carcinoma) | 68/6 | 162/9 | 0.300 | 0.573 |
TNM stage (I-II/III-IV) | 35/39 | 112/59 | 7.128 | 0.007 |
CEA(ng/mL) | 6.84 ± 2.32 | 5.50 ± 2.01 | 4.569 | 0.001 |
CYFRA21-1(ng/mL) | 3.80 ± 1.40 | 3.60 ± 1.01 | 1.259 | 0.209 |
Maximum tumor diameter (mm) | 29.44 ± 8.58 | 29.21 ± 8.32 | 0.197 | 0.844 |
Tumor volume (mm³) | 1288.67 ± 432.55 | 1286.67 ± 432.50 | 0.033 | 0.973 |
Long-axis to short-axis ratio | 0.48 ± 0.11 | 0.69 ± 0.20 | 8.488 | 0.001 |
Sphericity | 0.73 ± 0.10 | 0.71 ± 0.11 | 1.342 | 0.181 |
Radiomics energy value | 125.87 ± 35.48 | 125.43 ± 35.32 | 0.089 | 0.929 |
Gray-level co-occurrence matrix contrast | 23.66 ± 8.78 | 23.26 ± 8.71 | 0.329 | 0.742 |
Gray-level run-length matrix long-run emphasis | 0.33 ± 0.14 | 0.30 ± 0.11 | 1.780 | 0.073 |
Gray-level standard deviation | 18.86 ± 5.38 | 18.56 ± 5.20 | 0.410 | 0.681 |
Radiomics entropy | 4.53 ± 0.92 | 4.01 ± 0.77 | 4.569 | 0.001 |
Mean gray-level value (CT value, HU) | 45.77 ± 10.34 | 45.57 ± 10.01 | 0.142 | 0.887 |