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Table 3 Logistic regression results for the associations between gestational hypertension disease, thyroid dysfunction and neonatal outcomes (preterm birth and low birth weight)

From: Association between thyroid dysfunction and perinatal outcomes in women with gestational hypertension: a retrospective study

Characteristics preterm birth low birth weight
Unadjusted Adjusted Unadjusted Adjusted
severity of gestational hypertension (PIH, MPE, SPE)
 OR 4.914 4.360 4.119 4.023
 95% CI 2.354–10.255 2.050–9.271 2.084–8.144 1.933–8.372
P Value < 0.001 < 0.001 < 0.001 < 0.001
Onset time of gestational hypertension (EPE, LPE)
 OR 0.036 0.331 0.1108 0.097
 95% CI 0.011–0.112 0.009–0.110 0.041–0.283 0.033–0.282
 P Value < 0.001 < 0.001 < 0.001 < 0.001
Thyroid dysfunction
 OR 2.829 3.011 2.140 2.187
 95% CI 1.261–6.346 1.248–7.262 0.969–4.726 0.919–5.208
 P Value 0.012 0.014 0.060 0.077
Hypothyroidism
 OR 6.182 3.373 15.455 11.306
 95% CI 0.993–38.478 0.411–33.893 1.625–146.973 1.040–122.889
 P Value 0.051 0.242 0.017 0.046
Both FT3 and FT4 under the lower limit
 OR 1.448 1.496 1.493 1.531
 95% CI 1.064–1.971 1.000–2.237 1.103–2.021 1.049–2.234
 P Value 0.019 0.242 0.009 0.027
  1. Adjusted for age, gestational history, menstrual cycle, family history, and history of gestational hypertension
  2. PIH pregnant induced hypertension; MPE mild preeclampsia; SPE severe preeclampsia; EPE early onset preeclampsia; LPE late onset preeclampsia; FT3 free triiodothyronine; FT4 free thyroxine; TSH thyrotropic hormone