Skip to main content

Table 2 Comparisons of the clinical data from three groups of gestational hypertension according to the gestational age

From: Association between thyroid dysfunction and perinatal outcomes in women with gestational hypertension: a retrospective study

Characteristics PIH (N = 30) EPE (N = 57) LPE (N = 48) PIH vs. EPE PIH vs. LPE EPE vs. LPE
Age (year, mean ± SD) 30.43 ± 4.99 31.61 ± 5.34 31.34 ± 4.78 P = 0.304 P = 0.445 P = 0.785
Gestational weeks (at delivery) (week, mean ± SD) 38.53 ± 1.53 32.70 ± 3.95 38.01 ± 1.82 P < 0.001 P = 0.454 P < 0.001
Sex of baby (male, n%) 60.9% (14/23) 48.9% (23/47) 58.1% (25/43) P = 0.348 P = 0.830 P = 0.382
Neonatal birth weight (g, mean ± SD) 3192.41 ± 629.84
(N = 29)
1989.09 ± 712.97
(N = 44)
3028.48 ± 591.00
(N = 46)
P < 0.001 P = 0.288 P < 0.001
Hematocrit (L/L, mean ± SD) 0.38 ± 0.03 0.37 ± 0.03 0.37 ± 0.04 P = 0.795 P = 0.164 P = 0.175
Hemoglobin (g/L, mean ± SD) 123.40 ± 9.36 123.91 ± 12.03 119.83 ± 14.84 P = 0.857 P = 0.227 P = 0.102
Platelet (10^9/L, mean ± SD) 220.53 ± 40.22 208.10 ± 58.23 182.95 ± 66.72 P = 0.588 P = 0.011 P = 0.154
Fibrinogen (g/L, mean ± SD) 4.06 ± 0.74 3.67 ± 0.88 3.88 ± 0.64 P = 0.031 P = 0.338 P = 0.169
D-Dimer (mg/L, medians and interquartile ranges) 1.67 (1.16–2.82) 1.81 (1.09–2.39) 1.87 (1.27–2.66) P = 0.390 P = 0.966 P = 0.371
Brain natriuretic peptide (pg/mL, medians and interquartile ranges) 26.50 (17.25–65.50) 78.50 (25.75–228.00) 84 (32–186) P = 0.010 P = 0.005 P = 0.993
FT3 (pg/mL, medians and interquartile ranges) 3.56 (2.78–5.93) 3.48 (2.82–4.62) 4.32 (3.10–5.37) P = 0.659 P = 0.621 P = 0.105
FT4 (ng/dL, medians and interquartile ranges) 6.23 ± 1.06 6.21 ± 1.69 6.00 ± 1.89 P = 1.000 P = 0.885 P = 0.925
TSH (mIU/L, medians and interquartile ranges) 2.92 ± 0.93 2.64 ± 1.43 2.62 ± 1.26 P = 0.366 P = 0.347 P = 0.923
Triglyceride (mmol/L, medians and interquartile ranges) 1.95 ± 0.38 1.71 ± 0.82 1.77 ± 0.75 P = 0.165 P = 0.300 P = 0.730
Total cholesterol (mmol/L, mean ± SD) 2.54 (2.24–2.68) 2.49 (2.26–2.76) 2.55 (2.35–2.70) P = 0.989 P = 0.569 P = 0.518
Low density lipoprotein (mmol/L, mean ± SD) 0.98 (0.90–1.06) 0.95 (0.85–1.06) 0.93 (0.83–1.05) P = 0.655 P = 0.229 P = 0.477
High density lipoprotein (mmol/L, mean ± SD) 2.32 (1.79–3.26) 2.61 (1.63–4.20) 2.18 (1.67–3.05) P = 0.748 P = 0.534 P = 0.433
Rate of preterm birth (n%) 7.1% (2/28) 84.1% (37/44) 15.6% (7/45) P < 0.001 P = 0.486 P < 0.001
Rate of abortion (n%) 0 2.1% (1/48) 0 NS NS NS
Rate of induced labor (n%) 0 4.2% (2/48) 0 NS NS NS
Rate of fetal death (n%) 0 2.1% (1/48) 2.2% (1/46) NS NS P = 0.315
Thyroid dysfunction (n%) 60% (18/30) 71.9% (41/57) 56.3% (27/48) P = 0.258 P = 0.744 P = 0.094
Hypothyroidism (n%) 0 10.5% (6/57) 4.2% (2/48) NS NS P = 0.162
Subclinical hypothyroidism (n%) 20% (6/30) 15.8% (9/57) 8.3% (4/48) P = 0.804 P = 0.284 P = 0.072
FT3 under the lower limit (n%) 6.7% (2/30) 10.5% (6/57) 2.1% (1/48) P = 0.514 P = 0.680 P = 0.072
FT4 under the lower limit (n%) 16.7% (5/30) 19.3% (11/57) 25% (12/48) P = 0.339 P = 0.623 P = 0.556
FT3 and FT4 both under the lower limit (n%) 6.7% (2/30) 7.0% (4/57) 10.4% (5/48) P = 0.909 P = 1.000 P = 1.000
Hashimoto thyroiditis (n%) 13.3% (4/30) 8.8% (5/57) 4.2% (2/48) P = 1.000 P = 0.303 P = 0.267
hyperthyroidism (n%) 0 3.5% (2/57) 2.1% (1/48) NS NS P = 0.773
  1. A nominal 2-sided probability value < 0.05 was considered to indicate statistical significance, and adjustments were made for multiple comparisons in chi-square test and Kruskal Wallis Test (Padjust < 0.017)
  2. PIH pregnant induced hypertension; EPE early onset preeclampsia; LPE late onset preeclampsia; FT3 free triiodothyronine; FT4 free thyroxine; TSH thyrotropic hormone