The flow of the 504 potential respondents sampled through the trial is shown in Fig. 1. 84 (16.7%) of sampled individuals were not in the DSA, and thus no longer eligible, and further 55 (10.9%) could not be contacted within the study period. Amongst the 365 individuals contacted, 15 (3.0%) of individuals were unable to provide informed consent and 10 more (2.0%) declined to participate. Each arm was balanced by design on gender, age and location, and there were no statistical differences in the number of individuals being contacted or consenting to participate by arm (Table 1). Older and non-urban individuals were significantly more likely to be contacted, but there were no differences in willingness to participate once contacted.
Table 1 Respondent characteristics by response status and intention-to-treat arm
Of the 166 consenting respondents who were assigned to the CASI or ACASI arms, 29 (17%) did not complete the questionnaire as a self-interview (24/86 CASI [6.3%] vs 5/80 ACASI [27.9%]; \( {\chi}_1^2=13.5 \), p < 0.001). The most common reasons given for requesting CAPI rather than a self-interview were: inability to read or write (n = 15); eyesight problems (n = 9); and dislike of computers (n = 2). The proportion of individuals who declined self-interviews rose with age, from 2.1% amongst 18–29 year olds to 19.2% amongst 30–49 year olds to 27.3% amongst over 50 year-olds (Cuzick non-parametric trend test: Z = − 3.4, p = 0.001), but was not significantly different by gender (female: 19.1%; male: 15.6%, \( {\chi}_1^2=0.4 \), p = 0.55).
Across the three computer-based arms (CAPI, CASI, ACASI), interview duration varied systematically by arm among the 224 non-cognitive interview respondents (Fig 2). Under ITT, median duration was 8.3 min (interquartile range (IQR) 5.4–11.70) in the CAPI arm, 13.7 (IQR 13.7–20.1) in the CASI arm and 19.9 (IQR 14.6–30.9) in the ACASI arm; all distributions were right-skewed (skewness: 6.9; 5.0; 7.5). These differences were significant and moderately sized using a Wilcoxon rank-sum test: CAPI vs. CASI, Z = 4.9, p < 0.001, r = 0.40; CASI vs. ACASI, Z = 4.1, p < 0.001, r = 0.33. AT analysis results were qualitatively similar, although the 26 individuals opting-out of self-interview arms and into CAPI took a median of 12.4 min (IQR 12.4–19.2), significantly longer than those who did not opt-out (Wilcoxon Z = 2.6, p = 0.009, r = 0.21). There were no significant differences, either overall or within study arms, by age group or respondent gender.
Item non-response rates were generally higher in self-interview arms (Tables 2, 3, 4). In meta-analysis, self-interview respondents were significantly more likely to avoid responding to questions (Additional file 1: Figure S2). The mean percentage of respondents declining to answer was 4.4% in the interviewer-led arms versus 6.5% in the self-interview arms (mean difference: 2.1%, 95% confidence interval: 0.1–3.3%). However, this difference should be treated with caution given the high level of heterogeneity across questions: non-response was significantly (up to 10 percentage points) higher in self-interviews for several questions relating to respondents’ most-recent partner, but (non-significantly) lower for a range of other questions. Quantitatively, heterogeneity of effects for non-response was estimated to be very high (I
2=88.4, 95%CI: 85.4–90.7%).
Table 2 Item response rates for general sexual behaviours
Table 3 Item response rates for sexual behaviour questions not previously used in the surveillance
Table 4 Item response rates for partner-specific sexual behaviours with most-recent sexual partner
Amongst those who answered questions, in only a few cases were there significant differences between interviewer-led and self-interview arms (Tables 2, 3, 4). However, meta-analysis highlighted that self-interview respondents were more likely answer affirmatively to seven binary highly sensitive questions: mean percentage answering yes: 6.1% vs 4.2% for interviewer-led arms (Fig. 3). This difference was relatively small in absolute terms, but statistically significant (mean: 1.9%, 95% confidence interval [CI]: 0.3–3.6%). Heterogeneity of effects was estimated to be moderate (I
2=65%, 95% CI: 36–81%), although all effects were in the same direction. When we considered all 15 binary questions, the results were highly heterogeneous and no significant association was seen (Additional file 1: Figure S3). Effect sizes for both item non-response and affirmative responses were small to moderate, with a highest value of ϕ = 0.21 and mostly with values <0.10.
Our supplementary analysis comparing respondents’ EDM questionnaire responses to their prior surveillance questionnaire is presented in Additional file 1: Content S2. We did not find any significant differences either in surveillance responses or changes between last surveillance response and EDM response across EDM arms. Questions that should have time-invariant responses (e.g. age of sexual debut) did not significantly change between surveillance to EDM questionnaires.
Cognitive interviews
Acceptability and feasibility of sexual behaviour questions
In this area where sexual health surveillance has been conducted for over 10 years, few respondents found the topics covered unacceptable or difficult. Almost all respondents reported positive feelings towards answering sexual history questions that they had seen before, using terms such as ‘happy’, ‘no problem’, ‘comfortable’, ‘alright’ and ‘okay’. Difficulties in responding to sexual health questions revolved around question complexity – either due to long periods of recall or unclear question phrasing – or the inclusion of new topics that some respondents were not expecting:
“I don’t know how many different people I have had sex with in my lifetime. I am unable to count. When one grows up, you have sexual partners here and there. I did not save them in my memory because I didn’t know this information would be required at a later stage in my life” (male, 63 years old).
Some respondents, however, perceived some sexual behaviours as either socially acceptable or unacceptable:
“I didn’t have a problem to answer [meaning age at first sex]…I think I was at the right age to have sex” (male, 42 years old).
“It was difficult to answer this question [about anal sex]. It [anal sex] is for homosexuals…and practiced in prisons” (male, 34 years old).
Respondents did not generally find it difficult to recall details of specific sexual relationships, especially when discussing current sexual relationships which were going well. However a small number of participants found the partner-specific section difficult because it was depressing to talk about ex-partners; this suggests that participants may differentially underreport relationships that are concluded or undergoing strain:
“I felt unhappy…I didn’t really love one of them [meaning sexual partner]” (female, 51 years old).
Furthermore, a 75 year old female respondent repeatedly stated that she felt uncomfortable answering many questions about her sexual behaviour from the distant past with a much younger interviewer.
Respondents were also aware that reporting multiple recent partners might lead to more questions or more complex cognitive processes, with some commenting on their relief that they had few partners to report.
Differences from previous surveillance interviews
Half of those respondents who had previously completed AHRI sexual health questionnaires in annual surveillance using PAPI methods found it easier than before. The current version was seen as easier due to: (i) similar question wording to previous questionnaires; (ii) non-inclusion of more sensitive questions (e.g. self-reported HIV status); and (iii) the use of tablet computers. Amongst those in self-interview arms, the explicit option to not answer each question was appreciated. The other half of repeat respondents found the questionnaire harder than before, due to: (i) increased questionnaire length; (ii) perceived repetition of questions; and (iii) difficulty of recall, especially for older respondents.
The majority of participants had positive comments regarding the use of a computer in the EDM interview, such as “felt comfortable”, “felt no problem”, “felt good”, “happy about the computer”, “felt at ease after the practice”, “easy to use computer”, “comfortable with technology” and “happy about self-interview”.
Benefits and drawbacks of using electronic delivery methods
Tablets were seen as making interviews quicker and simpler than paper-based forms, as well as increasing confidentiality, trust and security – particularly for the self-interview arms.
“The use of computers made it easier…in the past [AHRI] used paper-based questionnaires, which compromised confidentiality. Interviewers could disclose our information to other people…but the use of computers protects our information” (Male, 29 years old, CAPI).
“No one can see our information on the tablet but paper questionnaires might get lost and found by other people who then read our confidential information” (Female, 20 years old, CAPI).
Participants in the self-interview arms broadly expressed excitement and comfort about answering questions themselves on the computer. However, some respondents reported that the self-interview methods placed more demand on the participant, since reading questions requires attention and focus; furthermore, one respondent, a 37 year old man, reported that the ACASI method felt slow.
In addition, some participants also expressed concerns about the use of tablets due to illiteracy, having lower education levels, or having eyesight problems.
The group discussion with study interviewers reinforced several themes from the cognitive interviews. These themes included respondent perceptions that self-interview methods were exciting and more confidential, although these factors led to slower interviews. Additionally, interviewers reported that self-interviews increased respondent trust in interviewers and the research process, since respondents had previously thought interviewers were making up some questionnaire questions (especially on sensitive topics), but now they could see that interviewers had not been misleading them. Interviewers also reported their preference for CAPI over other methods, since it was the fastest of all four methods, much lighter than carrying paper, and helped ensure data quality through skip patterns and error warnings.