Fig. 1

MLS0315771 significantly inhibited the growth of Gram-positive bacteria S. aureus and E. faecalis. A to D The planktonic cells of S. aureus CHS101, YUSA6, YUSA103 and YUSA129, and (E and F) E. faecalis OG1RF and EF16C166 were treated with 1/8 ×, 1/4 ×, 1/2 ×, and 1 × MIC of MLS0315771. The OD600 value of bacterial cells was measured at 1-h intervals for 24 h by automatic bacterial growth instrument. TSB without MLS0315771 was used as a negative control. Data are shown as Mean ± SD (n = 3). All experiments were performed in triplicate