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Figure 4 | Critical Care

Figure 4

From: Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury

Figure 4

Changes in calculated brain lactate-to-pyruvate (grey box plots) and lactate-to-glucose (white box plots) ratio determined by microdialysis reflecting influence of brain glucose on downstream cerebral metabolism in pre-defined brain glucose clusters, ranging from less than 1 mM to more than 9 mM in 1 mM buckets. At brain glucose levels exceeding 1 mM brain lactate-to-pyruvate and lactate-to-glucose were significantly decreased. Changes across the pre-defined brain glucose clusters compared with low brain glucose levels (<1 mM) were significant (*P < 0.001; analysis of variance on ranks, post hoc Dunn's test).

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