Abstract
Sixteen growing pigs were fed a vitamin E and selenium deficient diet; half of the animals (Group 2) were given a daily supply of vitamin E and selenium. After having been fed these diets for 53 days, the pigs were infected orally with minced colonic material from cases with typical swine dysentery. This exposure resulted in outbreaks of swine dysentery in both groups. The incubation times were, however, distinctly shorter and the clinical symptoms much more pronounced in Group 1 than in Group 2. The patho^morphological lesions in the colon also differed between the 2 groups. In the pigs of Group 1 evident pseudomembraneous lesions were observed in the spiral colon. In Group 2, the colonic alterations consisted predominantly of a catarrhal enteritis; pseudomembranes occurred in a minor part of colon in only 4 pigs. Both the clinical and the chemical observations and the pathological findings indicated a much better vitamin E and selenium balance in the pigs of Group 2. It is concluded that the treatment with vitamin E and selenium in Group 2 greatly increased resistance to swine dysentery.
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Alexander, T. J. L., P. D. Wellstead & M. J. Hudson: Studies of bacteria other than Treponema hyodysenteriae which may contribute to the lesion of swine dysentery. Congr. Int. Pig vet. Soc. 1976, Proc. Sect. L 1.
Andrews, E. D., W. J. Hartley & A. B. Grant: Selenium-responsive diseases of animals in New Zealand. N. Z. vet. J. 1968, 16, 3–17.
Doyle, L. P.: A Vibrio associated with swine dysentery. Amer. J. vet. Res. 1944, 5, 3–5.
Ellis, R. P. & M. W. Vorhies: Effect of supplemental dietary vitamin E on the serologic response of swine to an Escherichia coli bac- terin. J. Amer. vet. med. Ass. 1976, 168, 231–232.
Eriksen, L. & S. Andersen. Unders0gelser over eksperimentelt frem- kaldt svinedysenteri. (Experimental swine dysentery). Nord. Vet.-Med. 1970, 22, 161–173.
Espinasse, J.: Etiologie, pathogenic et therapeutique de I’enterite he- morragique du pore. (Etiology, pathogeny and treatment of hemorrhagic enteritis in the pig). Rec. Med. vet. 1973, 149, 1519–1530.
Glock, R. D.: The current status of swine dysentery. Feedstuffs 1972, 44, No. 34, p. 32 and 34.
Glock, R. D., K. J. Schwartz & D. L. Harris: Experimental immunization of pigs against Treponema hyodysenteriae. Congr. Int. Pig vet Soc. 1976, Proc. Sect. L 11.
Griffin, R. M., D. S. Fernie & R. W. A. Park: Campylobacter (Vibrio) coli - its possible role in the aetiology of swine dysentery. Congr. Int. Pig vet. Soc. 1976, Proc. Sect. L 3.
Hamdy, A. H. & M. W. Glenn: Transmission of swine dysentery with Treponema hyodysenteriae and Vibrio coli. Amer. J. vet. Res. 1974, 35, 791–797.
Harris, D. L.: Current status of research on swine dysentery. J. Amer, vet. med. Ass. 1974, 164, 809–812.
Harris, D. L. & R. D. Glock: Swine dysentery. J. Amer. vet. med. Ass. 1972, 160, 561–565.
Harris, D. L., R. D. Glock, C. R. Christensen & J. M. Kinyon: Swine dysentery. I. Inoculation of pigs with Treponema hyodysenteriae (new species) and reproduction of the disease. Vet. Med. 1972, 67, 61–64.
Hashim, S. A. & G. R. Schuttringer: Rapid determination of tocopherol in macro- and microquantities of plasma. Results obtained in various nutrition and metabolic studies. Amer. J. clin. Nutr. 1966, 19, 137–145.
Heinzerling, R. H., C. F. Nockels, C. L. Quarels & R. P. Tengerdy: Protection of chicks against E. coli infection by dietary supplementation with vitamin E. Proc. Soc. exp. Biol. (N. Y.) 1974, 146, 279–283.
Ihnat, M.: Fluorometric determination of selenium in foods. J. Ass. off. anal. Chem. 1974, 57, 368–378.
Jenkins, K. J. & M. Hidiroglou: A review of selenium/vitamin E responsive problems in livestock: A case for selenium as a feed additive in Canada. Canad. J. Anim. Sci. 1972, 52, 591–620.
Jolly, R. D.: A preliminary experiment on the effect of selenium on the growth rate of calves. N. Z. vet. J. 1960, 8, 13.
Nafstad, I., & S. Tollersrud: The vitamin E-deficiency syndrome in pigs. I. Pathological changes. Acta vet. scand. 1970,11, 452-480. Nordstoga, K,: Fibrinous colitis in swine, a manifestation of Shwartzman reaction? Vet. Rec. 1973, 92, 698.
Nordstoga, K., F. Saxegaard & E. Johannessen: Fibrin0s colitt hos gris. (Fibrinous colitis in swine). Nord. Vet.-Med. 1968, 20, 487–494.
Oksanen, H. E.: Studies on nutritional muscular degeneration (NMD) in ruminants. Acta vet. scand. 1965, 6, Suppl. 2.
Olson, L. D.: Clinical and pathological observations on the experimental passage of swine dysentery. Canad. J. comp. Med. 1974, 38, 7–13.
Schwartz, K. & R. D. Glock: Resistance to Treponema hyodysenteriae in passively immunized pigs. Congr. Int. Pig vet. Soc. 1976, Proc. Sect. L 12.
Spallholz, J. E., J. L. Martin, M. L. Gerlach & R. H. Heinzerling: Immunologic responses of mice fed diets supplemented with selenite selenium. Proc. Soc. exp. Biol. (N. Y.) 1973, 143, 685–689.
Teige, J. Jr., & K. Nordstoga: Experimental anaphylaxis in pigs. The influence of the vitamin E content in the feed. Acta vet. scand. 1977, 18, 210–220.
Teige, J., Jr., K. Nordstoga, M. Fjfilstad & I. Nafstad: The generalized Shwartzman reaction in pigs induced by diet and single injection of disintegrated cells or partially purified endotoxin from Escherichia coli. Acta vet. scand. 1973, 14, 92–106.
Tengerdy, R. P., R. H. Heinzerling & C. F. Nockels: Effect of vitamin E on the immune response of hypoxic and normal chickens. Infect. Immun. 1972, 5, 987–989.
Tengerdy, R. P., R. H. Heinzerling, G. L. Brown & M. M. Mathias: Enhancement of the humoral immune response by vitamin E. Int. Arch. Allergy 1973, 44, 221–232.
Trapp, A. L., K. K. Keahey, D. L. Whitenack & C. K. Whitehair: Vitamin E-selenium deficiency in swine: differential diagnosis and nature of field problem. J. Amer. vet. med. Ass. 1970, 157, 289–300.
Tvedten, H. W., C. K. Whitehair & R. F. Langham: Influence of vitamins A and E on gnotobiotic and conventionally maintained rats exposed to Mycoplasma pulmonis. J. Amer. vet. med. Ass. 1973, 163, 605–612.
Van Vleet, J. F., W. Carlton & H. J. Olander: Hepatosis dietetica and Mulberry heart disease associated with selenium deficiency in Indiana swine. J. Amer. vet. med. Ass. 1970, 157, 1208–1219.
Whiting, R. A., L. P. Doyle & R. S. Spray: Swine dysentery. Purdue Univ, agric. exp. Sta. Bull. 1921, 257, 1–15.
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Teige, J., Nordstoga, K. & Aursjø, J. Influence of Diet on Experimental Swine Dysentery. 1. Effects of A Vitamin E and Selenium Deficient Diet Supplemented with 6.8 % Cod Liver Oil. Acta Vet Scand 18, 384–396 (1977). https://doi.org/10.1186/BF03548436
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DOI: https://doi.org/10.1186/BF03548436