Skip to main content

The database of odor responses (DoOR) - Mapping the fruit fly's odor space

The database of odor responses (DoOR) is a repository for odor response measurements in the fruit fly Drosophila melanogaster. Olfactory receptors have broad, overlapping response spectra, and olfactory coding relies on activity patterns across the entire receptor array. It is therefore of interest to record receptor responses to a large set of odorant molecules, as opposed to only finding the respective best ligand.

The fruit fly has since long served as a model organism, resulting in a large number of odor response measurements that are available in the literature. Going beyond archiving the (odorant x receptor) response matrices from a growing number of studies on Drosophila olfaction, DoOR also provides a consensus matrix that integrates data from different studies using different techniques [1]. Such data integration leads to a larger odor response space than available from any single study.

Apart from encyclopedic applications, DoOR can be used e.g. to estimate odor (dis)similarity as "perceived" by Drosophila, and it has already served as realistic input data for a modelling study on odor processing in the antennal lobe [2]. DoOR is available both as a web-based GUI and as package for the R platform [3].


  1. Galizia CG, Münch D, Strauch M, Nissler A, Ma S: Integrating heterogeneous odor response data into a common response model: A DoOR to the complete olfactome. Chem Senses. 2010, 35: 551-63.

    PubMed Central  CAS  Article  PubMed  Google Scholar 

  2. Proske JH, Wittmann M, Galizia CG: Olfactory sensor processing in neural networks: lessons from modeling the fruit fly antennal lobe. Front Neuroeng. 2012, 5: 2-

    PubMed Central  Article  PubMed  Google Scholar 

  3. []

Download references

Author information

Authors and Affiliations


Rights and permissions

This article is published under an open access license. Please check the 'Copyright Information' section either on this page or in the PDF for details of this license and what re-use is permitted. If your intended use exceeds what is permitted by the license or if you are unable to locate the licence and re-use information, please contact the Rights and Permissions team.

About this article

Verify currency and authenticity via CrossMark

Cite this article

Strauch, M. The database of odor responses (DoOR) - Mapping the fruit fly's odor space. Flavour 3, O21 (2014).

Download citation

  • Published:

  • DOI:


  • Response Spectrum
  • Olfactory Receptor
  • Antennal Lobe
  • Response Matrice
  • Receptor Array