Adenoid cystic carcinoma intermingled with ductal carcinoma of the breast: a case report and review of the literature

Table 1 Review of mixed ACC cases in the literature^a

Study	Age, years	Histopathology	Surgery	Radiotherapy	Chemotherapy	ER/PR status
Mates et al. [4]	74	Micro-papillary invasive carcinoma mixed with ACC, 10 cm, N0	Mastectomy and full axillary clearance	No	Yes^b	Negative/positive
Noske et al. [6]	51	Spindle-cell carcinoma, melanoma, and ACC, 2.5 cm, N0	Lumpectomy and sentinel node biopsy	Yes^c	Yes^c	Negative
Cabibi et al. [3]	40	Small-cell carcinoma with ACC, 2.5 cm, N0	Lumpectomy and full axillary clearance	Yes	Yes	Negative
Righi et al. [5]	63	Ductal and intra-ductal carcinoma with ACC, 4.0 cm, N1	Mastectomy and full axillary clearance	Yes	Yes	Negative (both ACC and ductal component)
Present study	67	Ductal carcinoma and ACC, 1.7 cm, N0	Mastectomy and sentinel node biopsy	No	No	Negative (both ACC and ductal component)

^aACC: adenoid cystic carcinoma; ER/PR: estrogen receptor/progesterone receptor. ^bThe patient had bi-lateral cancer (right side was mixed ACC and micro-papillary, and left side was lobular invasive breast cancer). ^cBased on personal communication with A Noske.