In memoriam: Celso-Ramon Garcia, M.D. (1922–2004), reproductive medicine visionary

  • Jerome F StraussIII
  • Luigi MastroianniJr
Open Access


This article traces the career of Celso-Ramon Garcia (1922–2004), noted physician, educator, and internationally renowned pioneer in the field of reproductive endocrinology. His work helped to formulate oral contraceptives used by millions of women throughout the world. Garcia's research collaborators included Gregory Pincus and John Rock, who together finalized the landmark clinical data needed to secure initial FDA approval for "the pill" in 1960. In addition to Garcia's monumental work in contraceptive endocrinology, his scholarly interests encompassed physiology of the menopause, minimally invasive reproductive surgery, as well as psychological aspects of infertility. Closely identified with the University of Pennsylvania, Garcia was instrumental in establishing the first formal clinical program in reproductive biology and influenced countless young scientists whose training he supervised and mentored. His distinguished career was emblematic of the best of the medical profession, characterized by compassion, intellect, and a sincere desire to help others. Our manuscript outlines Garcia's wide range of interests, acknowledges his superior fund of knowledge, and honors his humanitarian spirit – all of which contributed to an impressive legacy of medical discoveries. The impact of Prof. Garcia's work will continue to be felt for many years.



  1. 1.
    Rock J, Pincus G, Garcia C-R: Effects of certain 19-nor steroids on the human menstrual cycle. Science. 1956, 124: 891-893.CrossRefGoogle Scholar
  2. 2.
    Pincus G, Garcia C-R, Rock J, Paniagua M, Pendleton A, Laraque F, Nicolas R, Borno R, Pean V: Effectiveness of an oral contraceptive; effects of a progestin-estrogen combination upon fertility, menstrual phenomena, and health. Science. 1959, 130: 81-3.CrossRefGoogle Scholar
  3. 3.
    Pincus G, Garcia C-R, Paniagua M, Shepard J: Ethynodiol diacetate as a new, highly potent oral inhibitor of ovulation. Science. 1962, 138: 439-440.CrossRefGoogle Scholar
  4. 4.
    Rosenfeld DL, Garcia C-R, Bullock W: An infertility data registry. Fertil Steril. 1978, 29: 112-114.CrossRefGoogle Scholar
  5. 5.
    Cutler WB, Garcia C-R, Edwards D: Menopause: A guide for women and the men who love them. 1985, W.W. Norton and Company, New YorkGoogle Scholar

Copyright information

© Strauss and Mastroianni; licensee BioMed Central Ltd. 2005

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Authors and Affiliations

  1. 1.Center for Research on Reproduction and Women's Health, Department of Obstetrics and GynecologyUniversity of PennsylvaniaPhiladelphiaUSA

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