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Table 5 Performance of cine-CMR Indices in Relation to Diastolic Dysfunction Severity - Diastolic Filling Rates

From: Impact of diastolic dysfunction severity on global left ventricular volumetric filling - assessment by automated segmentation of routine cine cardiovascular magnetic resonance

  Threshold Sensitivity Specificity Accuracy Positive
Predictive
Value
Negative
Predictive
Value
GRADE 1 (mild)       
   Peak Filling Rate 344 ml/sec† 5% (1/21) 83% (33/40) 56% (34/61) 13% (1/8) 62% (33/53)
   Normalized Peak Filling Rate 4.02/sec† 0% (0/21) 83% (33/40) 54% (33/61) 0% (0/7) 61% (33/54)
GRADE 2 (moderate)       
   Peak Filling Rate 344 ml/sec 7% (3/45) 83% (33/40) 42% (36/85) 30% (3/10) 44% (33/75)
   Normalized Peak Filling Rate 4.02/sec 9% (4/45) 83% (33/40) 44% (37/85) 36% (4/11) 45% (33/74)
GRADE 3 (severe)       
   Peak Filling Rate 344 ml/sec 56% (5/9) 83% (33/40) 78% (38/49) 42% (5/12) 89% (33/37)
   Normalized Peak Filling Rate 4.02/sec 67% (6/9) 83% (33/40) 80% (39/49) 46% (6/13) 91% (33/36)
  1. * Threshold of 77% diastole (to recover 80% stroke volume) based on previously established normative cutoff [15]
  2. † Matched to achieve equivalent specificity vs. DVR80