|
Stomach
|
Liver
|
Lung
|
---|
gen
|
M/F
|
M/F
|
M/F
|
φ
m
b
|
11.85
|
36.90
|
13.60
|
ca D
φ
> 0
|
1323
|
231
|
506
|
σ
c
|
77.56
|
33.51
|
34.72
|
τ
|
129.19
|
3.56
|
3.78
|
LRT
trans-lin
d
|
4.49
|
10.89
|
14.39
|
LRT
trans-con
|
5.91
|
18.12
|
15.70
|
ERR
0.025,φ
e
|
0.08 (-0.11, 0.23)
|
0.77 (0.18, 1.67)
|
0.79 (0.20, 2.01)
|
ERR
1,φ
|
0.00 (-0.06, 0.16)
|
0.95 (0.28, 1.99)
|
0.80 (0.19, 1.99)
|
Dmax
f
|
0.01
|
0.28
|
0.27
|
ERR
Dmax,φ
|
0.22 (-0.04, 0.61)
|
3.46 (1.00, 7.11)
|
3.38 (0.90, 8.43)
|
Dev
|
1676.81
|
1251.10
|
1039.00
|
Chi-sq
|
3397.32
|
2436.33
|
2728.08
|
df
|
2991
|
2991
|
2991
|
Excess
|
91.23
|
95.89
|
214.39
|
|
Colon
|
Uterus
|
All solid
|
gen
|
M/F
|
F
|
M/F
|
φ
m
b
|
43.98
|
26.91
|
43.86
|
ca D
φ
> 0
|
28
|
127
|
365
|
σ
c
|
26.69
|
275.88
|
11.89
|
τ
|
5.98
|
132.36
|
3.68
|
LRT
trans-lin
d
|
3.17
|
4.48
|
11.75
|
LRT
trans-con
|
3.20
|
4.48
|
16.78
|
ERR
0.025,φ
e
|
0.58 (-0.25, 1.85)
|
0.25 (-0.09, 1.13)
|
0.27 (0.07, 0.51)
|
ERR
1,φ
|
0.07 (-0.49, 1.71)
|
0.00 (-0.23, 1.06)
|
0.30 (0.03, 0.63)
|
Dmax
f
|
0.17
|
0.01
|
0.27
|
ERR
Dmax,φ
|
1.64 (-0.60, 6.10)
|
0.77 (-0.54, 5.35)
|
1.19 (0.41, 2.06)
|
Dev
|
716.79
|
634.49
|
2121.27
|
Chi-sq
|
3473.93
|
1051.37
|
2765.95
|
df
|
2991
|
1512
|
2991
|
Excess
|
8.24
|
19.99
|
78.00
|
-
a0 – 20 mSv subcohort, Excess Relative Risk ERR = σDφ with τ ≥ 0 and σ,τ constrained by 1 + ERR ≥ 0 for all data cells; for Dφ see Table 1. The linear model is nested by τ = 0; the control model is nested by σ = 0.
-
bchosen in the range 5 – 44 years. to minimise transient model Deviance; where italicised φm minimises Dev subject to ERR ≥ 0, equivalent to σ ≥ 0.
-
cAt φm, σ and τ are the fitted Maximum Likelihood Estimate parameter values.
-
dAt φm, the likelihood ratio test LRTtrans-lin compares the transient with the linear model and LRTtrans-con compares the transient model with the control model. Each LRT is χ2 distributed on 1 degree of freedom.
-
eAt φm, ERRD,φ is the Excess Relative Risk at Dφ = D, with 95% Profile Likelihood Confidence Interval.
-
fAt φm, Dmax = 1/τ is the value of D which maximises ERRD,φ
-
gn/a indicates no lower limit could be calculated with 1 + ERR ≥ 0
- Other definitions and total cases as Table 1.