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Table 2 Potency estimate and parameters derived from linear regression with their statistical comparison of generics versus innovator by Curve Fitting Analysis

From: Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics

Product r2 Intercept [95% CI] P-value Slope [95% CI] P-value Potency Estimate (%)
AMK-BMS 0.99 9.006 [8.646 to 9.366] 0.8799 3.884 [3.619 to 4.148] 0.6559 100.00
AMK-Carlon 0.99 9.082 [8.651 to 9.514]   3.789 [3.472 to 4.105]   99.83
AMK-Gencol 0.99 9.238 [8.738 to 9.737]   3.731 [3.365 to 4.098]   100.51
AMK-Pisa 0.99 9.244 [8.860 to 9.629]   3.698 [3.416 to 3.980]   100.31
AMK-Scalpi 0.99 8.920 [8.552 to 9.287]   3.935 [3.665 to 4.204]   99.77
AMK-Sigma 0.99 8.945 [8.575 to 9.315]   3.926 [3.655 to 4.198]   99.89
GNT-SP 0.99 10.44 [10.16 to 10.720] 0.9472 3.881 [3.594 to 4.167] 0.9984 100.00
GNT-Abbott 0.98 10.00 [9.557 to 10.440]   4.150 [3.695 to 4.605]   99.72
GNT-Az pharma 0.98 10.02 [9.576 to 10.460]   4.021 [3.570 to 4.473]   99.68
GNT-Biochemie 0.98 10.08 [9.668 to 10.500]   4.038 [3.613 to 4.463]   99.75
GNT-Biogenta 0.98 10.13 [9.736 to 10.510]   3.925 [3.526 to 4.324]   99.74
GNT-Colmed 0.98 10.13 [9.701 to 10.550]   3.918 [3.483 to 4.354]   99.74
GNT-Genfar 0.99 10.04 [9.697 to 10.380]   4.091 [3.738 to 4.443]   99.73
GNT-Lab America 0.99 10.09 [9.708 to 10.470]   4.143 [3.754 to 4.532]   99.79
GNT-Labinco 0.99 10.11 [9.749 to 10.470]   3.994 [3.623 to 4.366]   99.76
GNT-La Sante 0.98 10.11 [9.668 to 10.550]   4.106 [3.655 to 4.558]   99.80
GNT-Memphis 0.98 10.15 [9.694 to 10.610]   3.935 [3.465 to 4.406]   99.77
GNT-MK 0.98 10.09 [9.672 to 10.510]   4.146 [3.715 to 4.577]   99.68
GNT-Ophalac 0.98 10.02 [9.571 to 10.460]   4.006 [3.549 to 4.463]   99.68
GNT-Pentacoop 0.98 10.13 [9.690 to 10.560]   3.962 [3.514 to 4.409]   99.76
GNT-Recipe 0.98 10.10 [9.700 to 10.510]   3.926 [3.512 to 4.340]   99.72
GNT-Scalpi 0.98 10.13 [9.720 to 10.540]   3.919 [3.501 to 4.337]   99.74
GNT-Sigma 0.98 10.36 [9.889 to 10.830]   4.109 [3.629 to 4.590]   100.02
VAN-Lilly 0.99 6.320 [5.715 to 6.924] 0.0201 5.562 [5.082 to 6.042] 0.8594 100.00
VAN-Abbott 0.99 5.782 [5.248 to 6.316]   5.558 [5.134 to 5.982]   98.51
VAN-APP 0.99 6.281 [5.734 to 6.828]   5.359 [4.925 to 5.793]   99.30
VAN-Proclin 0.99 6.388 [5.721 to 7.054]   5.462 [4.933 to 5.991]   99.90