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Table 2 Comparision of randomized control trials indexed in CNKI database before and after 2010 in terms of CONSORT items

From: The quality of reports of randomized clinical trials on traditional Chinese medicine treatments: a systematic review of articles indexed in the China National Knowledge Infrastructure database from 2005 to 2012

Criterion Item no. No. (%) of trials in which the item was clearly reported P value
   All (n = 6994) Before 2010 (n = 4133) After 2010 (n = 2861)  
Title and abstract 1a 56 (0.80) 23 (0.56) 33 (1.15) 0.006
  1b 5852 (83.67) 3505 (84.81) 2347 (82.03) 0.002
Background and objectives 2a 2028 (29.00) 1021 (24.71) 1007 (35.20) <0.001
  2b 410 (5.86) 263 (6.36) 147 (5.14) 0.032
Trial design 3a 277 (3.96) 184 (4.45) 93 (3.25) 0.011
Participants 4a 3925 (56.12) 2058 (49.79) 1867 (65.26) <0.001
  4b 4938 (70.60) 2664 (64.46) 2274 (79.48) <0.001
Interventions 5 5699 (81.48) 3342 (80.86) 2357 (82.38) 0.107
Outcomes 6a 6176 (88.30) 3626 (87.73) 2550 (89.13) 0.074
Sample size 7a 20 (0.29) 8 (0.19) 12 (0.42) 0.082
Sequence generation 8a 1137 (16.26) 569 (13.77) 568 (19.85) <0.001
  8b 117 (1.67) 78 (1.89) 39 (1.36) 0.093
Allocation concealment mechanism 9 48 (0.69) 30 (0.73) 18 (0.63) 0.63
Implementation 10 36 (0.51) 31 (0.75) 5 (0.17) 0.001
Blinding 11a 268 (3.83) 197 (4.77) 71 (2.48) <0.001
  11b 8 (0.11) 5 (0.12) 3 (0.10) 1.000
Statistical methods 12a 4686 (67.00) 2604 (63.00) 2082 (72.77) <0.001
Flow diagram 13a 20 (0.29) 11 (0.27) 9 (0.31) 0.709
  13b 246 (3.52) 141 (3.41) 105 (3.67) 0.564
Recruitment 14a 5198 (74.32) 2899 (70.14) 2299 (80.36) <0.001
Baseline data 15 445 (6.36) 232 (5.61) 213 (7.44) 0.002
Numbers analyzed 16 127 (1.82) 80 (1.94) 47 (1.64) 0.367
Outcomes and estimation 17a 89 (1.27) 58 (1.40) 31 (1.08) 0.241
  17b 21 (0.30) 8 (0.19) 13 (0.45) 0.050
Harms 19 1830 (26.17) 1096 (26.52) 734 (25.66) 0.42
Limitations 20 572 (8.18) 356 (8.61) 216 (7.55) 0.11
Generalizability 21 187 (2.67) 115 (2.78) 72 (2.52) 0.498
Interpretation 22 6473 (92.55) 3806 (92.09) 2667 (93.22) 0.077
Registration 23 1 (0.01) 0 (0) 1 (0.03) 0.853
Protocol 24 1 (0.01) 0 (0) 1 (0.03) 0.853
Funding 25 413 (5.91) 270 (6.53) 143 (5.00) 0.007