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Table 2 Summary of the comparison of the diagnoses based on the biopsy, the endoscopy, the EUS, Paris classification, ER specimens with the gold standard

From: Diagnosis and staging of superficial esophageal precursor based on pre-endoscopic resection system comparable to endoscopic resection

  Final Diagnosis P value
  Pathological diagnosis Invasive depth  
  LGIN MGIN HGIN ESCC Mucosa Submucosa  
Biopsy diagnosis <0.05
LGIN 0 4 5 3 NA NA  
MGIN 0 11 7 5 NA NA  
HGIN 0 0 94 57 NA NA  
ESCC 0 0 0 31 NA NA  
EUS <0.05
Mucosa NA NA NA NA 143 11  
Submucosa NA NA NA NA 46 17  
Paris classification <0.05
0-IIa 0 17 48 66 NA NA  
0-IIb 0 14 89 150 NA NA  
0-IIc 0 0 0 1 NA NA  
Noninvasive 0 13 91 52 NA NA  
Invasive 0 2 15 44 NA NA  
Endoscopic diagnosis <0.05
LGIN 0 7 11 2 NA NA  
MGIN 0 3 27 6 NA NA  
HGIN 0 4 61 53 NA NA  
ESCC 0 1 7 35 NA NA  
ER diagnosis <0.05
LGIN 0 5 7 1 NA NA  
MGIN 0 10 20 0 NA NA  
HGIN 0 2 77 3 NA NA  
ESCC 0 0 2 92 NA NA  
Pre-ER diagnosis <0.05
LGIN 0 0 0 0 NA NA  
MGIN 0 9 6 0 NA NA  
HGIN 0 4 93 0 NA NA  
ESCC 0 2 7 96 NA NA  
  1. LGIN: low-grade intra-epithelia neoplasia; MGIN: middle-grade intra-epithelia neoplasia; HGIN: high-grade intra-epithelia neoplasia; ESCC: esophageal squmous cell carcinoma.