Figure 14
From: Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells

ELISA measurement of VEGF secretion. ELISA was performed as described in Methods. MSC from each age were grown to confluence in parallel and VEGF measured in the medium 24h after replacement. Significantly less VEGF was secreted from cells taken from mice at age 26 mo (n=4; p<0.02).