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Biotechnology for Biofuels

, 12:83 | Cite as

Correction to: QTL analysis reveals genomic variants linked to high-temperature fermentation performance in the industrial yeast

  • Zhen Wang
  • Qi Qi
  • Yuping LinEmail author
  • Yufeng Guo
  • Yanfang Liu
  • Qinhong WangEmail author
Open Access
Correction
  • 152 Downloads

Correction to: Biotechnol Biofuels (2019) 12:59  https://doi.org/10.1186/s13068-019-1398-7

Shortly after publication of the original article [1], the authors noticed a few errors which are outlined below:

In Table 2, the SNP mutation for RXT2 in ScY01α-tp should be 331 C>G. As shown in Additional file 5: Dataset S3, the position of the SNP in RXT2 is NC_001134.8:435,368, and annotated as G>C according to the chromosome sequence. Since the coding sequence of RXT2 (systematic gene name: YBR095C) is on the Crick strand, the SNP should be described as C>G at the 331 position according to the coding sequence. The corrected Table 2 is provided here.
Table 2

Genes with nonsynonymous variants in two major and two minor QTLs

QTLs

Chr

Start (bp)

End (bp)

Length (bp)

LOD score

Affected gene

Mutation (S288c genome as a reference)

ScY01α-tp

W65a-sp

Major QTLs

 QTL1

II

408,800

553,700

144,900

17

RXT2

331 C>G (R111G)

Wild type

VID24

154 C>T (P52S)

Wild type

 QTL2

XII

595,800

633,500

37,700

300

ECM22

1954 G>A (G652S)

Wild type

VPS34

1773 C>G (D591E)

Wild type

CSC1

1126 C>A (Q376K)

Wild type

Minor QTLs

 QTL3

XV

174,500

184,900

10,400

272

IRA2

Wild type

7222 C>A (P2408T)

AVO1

Wild type

2558 T>C (V853A)

 QTL4

XVI

228,200

238,100

9900

155

DAP1

Wild type

115 G>A (V39I)

The gene ECM24, which was misspelled six times in the original article, should be ECM22 in the following contents: the Abstract, the last paragraph of the Background, sentence 5 and 6 in paragraph 1 under the heading “Characterization of key causative gene alleles for improving high-temperature fermentation of the industrial yeast”, the last paragraph of the Discussion and the Conclusions.

Page 11, paragraph 3 under the heading “Characterization of key causative gene alleles for improving high-temperature fermentation of the industrial yeast”, sentence 8 should be: “By contrast, membrane fluidities of these cells at the stationary phase among the reciprocal hemizygotes of DAP1 and the control strains were similar.”

In the following two contexts, the word “thermosensitive” should be “thermotolerant”. Page 4, paragraph 2 under the heading “Screening of the superior, inferior and random pools of segregants for genome sequencing”, sentence 7 should be: “Thus, ten segregants showing the 10 highest OD600 ratios (1.37 to 2.17) than ScY01α-tp were selected as the most thermotolerant segregants and assembled in the superior pool.” Sentence 3 in the Fig. 3b legend should be: “Ten segregants showing the 10 highest OD600 ratios (1.37 to 2.17) than ScY01α-tp were selected as the most thermotolerant segregants and assembled in the superior pool.”

In sentence 2 of the Fig. 4 legend, the strain name “W65a-tp” should be “W65a-sp”. In sentence 4 of the Fig. 4 legend, the Ref. [30] should be [25].

Page 14, Methods paragraph 2, sentence 5 should be: “Starting OD600 used in all the experiments was 0.5.”

The description “(hours 0, 8, 12, 18, 24 30 36 42 and 48)” should be “(hours 0, 4, 8, 12, 18, 24, 30, 36, 42 and 48)” in the following two contents: sentence 1 in the Fig. 6 legend and sentence 5 in the last paragraph of the Methods.

These changes will in no manner affect the outcome/interpretation of the experiments as described in the original publication. The authors apologize for any inconvenience caused.

Notes

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Reference

  1. 1.
    Wang Z, Qi Q, Lin Y, Guo Y, Liu Y, Wang Q. QTL analysis reveals genomic variants linked to high-temperature fermentation performance in the industrial yeast. Biotechnol Biofuels. 2019;12:59.  https://doi.org/10.1186/s13068-019-1398-7.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors and Affiliations

  1. 1.CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjinChina
  2. 2.University of Chinese Academy of SciencesBeijingChina

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