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Analysis of Placental Vascularization by Means of 3D Power Doppler in Women Pregnant Following Oocyte Donation

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Abstract

Objective

To analyze the differences in placental perfusion in pregnancies following oocyte donation compared to spontaneous pregnancies.

Participants and Methods

A total of 33 patients who became pregnant after oocyte donation are studied and compared to 42 spontaneously pregnant participants. A 3-dimensional Power Doppler is used to obtain 3 placental volumes. Of each volume, 3 portions are analyzed in the form of a spherical “placental biopsy.” Four vascularization rates are applied, using the virtual organ computer-aided analysis (VOCAL) method: grey index (GI), vascularization index (VI), flow index (FI), and vascularization-flow index (VFI).

Results

Vascular alterations are demonstrated, manifested by a lower IG and a significantly higher IV in the group of spontaneous pregnancies (GI P = .001; (VI) P = .039) and is almost statistically significant in comparison to the IVF (P = .051).

Conclusions

Placental perfusion in pregnancies obtained following oocyte donation is deficient in comparison to spontaneous pregnancies.

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Authors and Affiliations

  1. Bernabeu Institute of Fertility and Gynecology, Avda de la Albufereta, 31, 03016, Alicante, Spain

    F. Sellers López MD, J. M. Lozano, A. Palacios & R. Bernabeu MD

  2. Family Medicine Cathedra, Miguel Hernandez University, Elche, Spain

    Domingo Orozco-Beltran MD & Vicente Gil-Guillen MD

  3. Reproductive Health Cathedra, Miguel Hernandez University, Elche, Spain

    R. Bernabeu MD

Authors
  1. F. Sellers López MD
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  2. Domingo Orozco-Beltran MD
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  3. Vicente Gil-Guillen MD
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  4. J. M. Lozano
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  5. A. Palacios
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  6. R. Bernabeu MD
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Correspondence to F. Sellers López MD.

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Sellers López, F., Orozco-Beltran, D., Gil-Guillen, V. et al. Analysis of Placental Vascularization by Means of 3D Power Doppler in Women Pregnant Following Oocyte Donation. Reprod. Sci. 17, 754–759 (2010). https://doi.org/10.1177/1933719110371013

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  • DOI: https://doi.org/10.1177/1933719110371013

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