The study draws upon a mail survey of 762 US investigators. Investigators provide a number of reasons for their participation in clinical trials, but this study underscores medical innovation as the most important stimulus. Among other reasons for participating in clinical trials, the prospect of additional financial remuneration plays an important role, especially for office-based investigators. Clinical investigators may be tempted to provide socially valued responses, such as those relating to medical innovation, over more mundane considerations such as finances, as the reason for their taking part in clinical trials. Still, medical innovation figures prominently as a reason why investigators of all types participate in phase 3 clinical trials. This is important in understanding how to recruit experienced investigators, as well as physicians who may be potentially new clinical investigators.
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Identify how to recruit experienced investigators, as well as physicians who may be potentially new clinical investigators.
This CME activity is designed for all involved in the design/implementation and analysis of clinical trials
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Class H, Poli L. Connecting the dots. Pharm Exec. 2007;(1):56–58.
Glass H, DiFrancesco J. Understanding site performance differences in multinational phase III clinical trials. Int J Pharm Med. 2007;21(4): 279–286.
Glass H, Beaudry D. The demographic, practice, and prescribing characteristics of US clinical investigators. Drug Inf J. 2007;41:641–647
Getz K. Mapping the clinical investigator landscape. Presented at the 43rd annual D1A meeting; Atlanta, GA, June 18.2007.
Glass H, Kane R. Why investigators take part in clinical trials. Appl Clin Trials. 2000;9(6):46–54.
Glass H. The marketplace for clinical grants. Monitor. 2005;19(4):69–74.
Glass H. Do clinical grant payment practices in phase 3 clinical trials influence subsequent clinical investigator prescribing behavior? Dis Manage. 2004;7(1):3–17
US Food and Drug Administration. Database, Bioresearch Monitoring Information System File. Available at: http://www.accessdata.fda.gov/scripts/cder/bmis/index.cfm.
Fabrigar LR, Wegener DT, MacCallum RC, Strahan EJ. Evaluating the use of exploratory factor analysis in psychological research. Psychological Methods. 1999;(4):272–299.
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Gloss, H.E. The Importance of Medical Innovation in an Investigator’s Decision to Take Part in Clinical Trials. Ther Innov Regul Sci 42, 537–543 (2008). https://doi.org/10.1177/009286150804200602
- Principal investigator
- Phase 3 clinical trial
- Medical innovation
- Financial considerations
- Study sponsor and conduct