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Mathematical Derivation of Therapeutic Index Based on hERG IC50 Taking Into Account Fraction Unbound in Plasma and Clinical Cmax

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Correspondence to Ryan M. Fryer PhD.

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Fryer, R.M. Mathematical Derivation of Therapeutic Index Based on hERG IC50 Taking Into Account Fraction Unbound in Plasma and Clinical Cmax. Ther Innov Regul Sci 46, 519–520 (2012) doi:10.1177/0092861512456285

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