Centers for Education and Research on Therapeutics (CERTs)


The Centers for Education and Research on Therapeutics (CERTs) program is a national initiative authorized by the Food and Drug Modernization Act of 1997 (FDAMA) (Public Law 105-115) as a public-private partnership. The program is administered by the Agency for Healthcare Research and Quality (AHRQ) in close collaboration with the Food and Drug Administration (FDA). Seven research centers and a coordinating center together with representatives AHRQ, FDA, the National Institutes of Health, the pharmaceutical industry, consumers, and at-large members collaborate on a steering committee led by an independent chairperson. Duke University Medical Center serves as a coordinating center to foster collaboration on research and educational themes and topics of importance in therapeutics. The CERTs vision is to serve as a trusted national resource for people seeking to improve their health through the best use of medical therapies. Two research projects are described that focus on assuring use of life-saving therapies (eg, beta-blockers for treatment of congestive heart failure) and avoiding misuse of high-risk therapies (eg, medications that may cause a fatal cardiac arrhythmia).

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Author information

Correspondence to Judith M. Kramer MD, MS.

Additional information

This project was supported by an Agency for Healthcare Research and Quality (AHRQ) Centers for Education and Research on Therapeutics cooperative agreement (Grant # HS 10548).

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Kramer, J.M., Bosco, L.A. & Califf, R.M. Centers for Education and Research on Therapeutics (CERTs). Ther Innov Regul Sci 36, 717–723 (2002).

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Key Words

  • CERTs
  • Therapeutics
  • AHRQ
  • Drugs