Abstract
Objective
Knowledge of the procedural requirements for international research is not widely disseminated to investigators involved in the administration of a federal grant with a foreign component. The purpose of this article is to highlight the major challenges in administrative, procedural, and equipment management aspects of grant implementation when federal funding is involved in international collaborative research.
Methods
The author describes the procedural requirements for international research from the time of priority score receipt to the implementation of the grant.
Results
There is tremendous promise for rewarding experiences in international research projects due to the collaboration, mutual learning, and cultural bridging that intrinsically occur. However, there are also inherent cross-national procedural requirements that can be demanding in time and effort for the investigator and other stakeholders of the grant.
Conclusions
It is hoped that awareness of these difficulties and demystification of the process for future investigators can minimize the potential encumbrances in such international research.
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References
Beasley JW, Starfield B, van Weel C, et al: Global health and primary care research. J Am Board Fam Med 2007; 20: 518–526
Belkin GS, Fricchione GL: Internationalism and the future of academic psychiatry. Acad Psychiatry 2005; 29: 240–243
Cohen LK: Addressing global health research in the national interest. J Public Health Dent 2007; 67: 67–68
Fauci AS: The global challenge of infectious diseases: the evolving role of the national institutes of health in basic and clinical research. Nat Immunol 2005; 6: 743–747
Maziak W: Global health research: science aid program could be set up to help researchers in developing countries. BMJ 2001; 322: 173
Fogarty International Center funds institutions to fight TB and AIDS. J Investig Med 2006; 54: 53
Fogarty International Center expands “Framework Programs in Global Health.” J Investig Med 2007; 55: 9
Breman JG, Bridbord K, The John E. Fogarty International Center: Collaborative Projects in International Environmental and Occupational Health. Partnerships and Progress. Int J Occup Environ Health 1999; 5: 198–202
Vastag B: World health focus of Fogarty International Center. JAMA 2002; 287: 2063–2064
Gill TM, McDermott MM, Ibrahim SA, et al. Getting funded: career development awards for aspiring clinical investigators. J Gen Intern Med 2004; 19: 472–478
Khalsa PS, Pearson NJ: Financial support for research training and career development in complementary and alternative medicine from the national institutes of health. J Manipulative Physiol Ther 2007; 30: 483–490
Motto D, Roltsch M, Poncz M: Mechanisms for mentored career development: the NIH research career awards and other national awards. Hematology Am Soc Hematol Educ Program 2007; 2007: 504–508
Kotchen TA, Lindquist T, Malik K, et al: NIH peer review of grant applications for clinical research. JAMA 2004; 291: 836–843
Berg KM, Gill TM, Brown AF, et al: Demystifying the NIH grant application process. J Gen Intern Med 2007; 22: 1587–1595
Dawson L, Kass NE: Views of US researchers about informed consent in international collaborative research. Soc Sci Med 2005; 61: 1211–1222
Geller SE, Patel A, Niak VA, et al: Conducting international collaborative research in developing nations. Int J Gynaecol Obstet 2004; 87: 267–271
Hyder AA, Wali SA: Informed consent and collaborative research: perspectives from the developing world. Dev World Bioeth 2006; 6: 33–40
Jin K, Lombardi DA, Courtney TK, et al: The challenge of cross-cultural collaborative research: lessons learnt from a pilot case-crossover study of severe occupational hand trauma in the People’s Republic of China. Inj Prev 2007; 13: 133–136
Lavery JV: Putting international research ethics guidelines to work for the benefit of developing countries. Yale J Health Policy Law Ethics 2004; 4: 319–336
Robison VA: Some ethical issues in international collaborative research in developing countries. Int Dent J 1998; 48: 552–556
Rosser WW, Culpepper L, Lam CL, et al: Guidelines for international collaborative research. Fam Pract 1997; 14: 330–334
Simon C, Mosavel M, van Stade D: Ethical challenges in the design and conduct of locally relevant international health research. Soc Sci Med 2007; 64: 1960–1969
White MT: Guidelines for IRB review of international collaborative medical research: a proposal. J Law Med Ethics 1999; 27: 87–94
Wichman A, Smith J, Mills D, et al: Collaborative research involving human subjects: a survey of researchers using international single project assurances. Irb 1997; 19: 1–6
Patrullo EL, Levine RJ: How general an assurance? IRB 1981; 3: 8–9
Sugarman J: The role of institutional support in protecting human research subjects. Acad Med 2000; 75: 687–692
U.S. Department of Health and Human Services, Office for Human Research Protections (OHRP): Step-by-Step Instructions for Registering an Institutional Review Board (IRB) or Independent Ethics Committee (IEC), 2008. Available at www.hhs.gov/ohrp/humansubjects/assurance/regirbi.htm
Feehally J: The impact of the OFAC regulations on the work of ISN. Kidney Int 2006; 70: 1531–1532
University of North Carolina at Chapel Hill: Export Control, 2008. Available at http://www.unc.edu/campus/Export_Control/index.html#top
Funke OUS: Chemical program: purpose, challenges, and evolution. Politics Life Sci 2001; 20: 175–187
Bertha SL: Academic research: policies and practice. J Ethnopharmacol 1996; 51: 59–73
Boyd P Health research and the Data Protection Act 1998. J Health Serv Res Policy 2003; 8(suppl l):Sl:24-27
Girsberger MA: Transparency measures under patent law regarding genetic resources and traditional knowledge: disclosure of source and evidence of prior informed consent and benefit-sharing. J World Intellect Prop 2004; 7: 451–489
Cressey D: Exchange rate hits US researchers. Nature 2007; 450: 1136
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The author acknowledges the support from NICHD (Grant K08 HD051894) and FPR-UCLA Center for Culture, Brain, and Development. At the time of submission, the author disclosed no competing interests.
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Loo, K.K. Procedural Challenges in International Collaborative Research. Acad Psychiatry 33, 229–233 (2009). https://doi.org/10.1176/appi.ap.33.3.229
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DOI: https://doi.org/10.1176/appi.ap.33.3.229