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Stable free radicals generated during the oxidation of 4-alkyl Hantzsch 1,4-dihydropyridines with nitrosonium — EPR evidence

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Abstract

Stable free radicals were observed by EPR technique during the oxidation of 4-isopropyl and 4-isobutyl Hantzsch 1,4-dihydropyridines with nitrosonium tetrafluoroborate (NO+BF-4) in anhydrous and anaerobic acetonitrile at room temperature. These free radicals were assigned to diisopropyl aminoxyl and diisobutyl aminoxyl, respectively. A whole mechanism for the oxidation was suggested.

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Authors and Affiliations

  1. National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, China

    L.-M. Wu, W. Chen & Z.-L. Liu

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  1. L.-M. Wu
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  2. W. Chen
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  3. Z.-L. Liu
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Wu, LM., Chen, W. & Liu, ZL. Stable free radicals generated during the oxidation of 4-alkyl Hantzsch 1,4-dihydropyridines with nitrosonium — EPR evidence. Research on Chemical Intermediates 27, 219–224 (2001). https://doi.org/10.1163/156856701300356437

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