The European Physical Journal Special Topics

, Volume 223, Issue 10, pp 1937–1947

Opto-acoustic sensing of fluids and bioparticles with optomechanofluidic resonators

Regular Article Hollow Core Resonators

DOI: 10.1140/epjst/e2014-02237-4

Cite this article as:
Zhu, K., Han, K., Carmon, T. et al. Eur. Phys. J. Spec. Top. (2014) 223: 1937. doi:10.1140/epjst/e2014-02237-4
Part of the following topical collections:
  1. Taking Detection to the Limit: Biosensing with Optical Microcavities

Abstract

Opto-mechano-fluidic resonators (OMFRs) are a unique optofluidics platform that can measure the acoustic properties of fluids and bioanalytes in a fully-contained microfluidic system. By confining light in ultra-high-Q whispering gallery modes of OMFRs, optical forces such as radiation pressure and electrostriction can be used to actuate and sense structural mechanical vibrations spanning MHz to GHz frequencies. These vibrations are hybrid fluid-shell modes that entrain any bioanalyte present inside. As a result, bioanalytes can now reflect their acoustic properties on the optomechanical vibrational spectrum of the device, in addition to optical property measurements with existing optofluidics techniques. In this work, we investigate acoustic sensing capabilities of OMFRs using computational eigenfrequency analysis. We analyze the OMFR eigenfrequency sensitivity to bulk fluid-phase materials as well as nanoparticles, and propose methods to extract multiple acoustic parameters from multiple vibrational modes. The new informational degrees-of-freedom provided by such opto-acoustic measurements could lead to surprising new sensor applications in the near future.

Copyright information

© EDP Sciences and Springer 2014

Authors and Affiliations

  1. 1.Department of Mechanical Science and EngineeringThe University of Illinois at Urbana-ChampaignUrbanaUSA
  2. 2.Department of Biomedical EngineeringUniversity of MichiganAnn ArborUSA
  3. 3.Mechanical EngineeringTechnion — Israel Institute of Technology, Technion CityHaifaIsrael

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