The European Physical Journal Special Topics

, Volume 143, Issue 1, pp 125–132 | Cite as

On the study of the dynamical aspects of parasitemia in the blood cycle of malaria

  • R.M. Zorzenon dos Santos
  • S. T.R. Pinho
  • C. P. Ferreira
  • P. C.A. da Silva


Malaria is an important cause of morbidity and mortality worldwide. One striking aspect regarding malaria is the fact that individuals living in endemic areas do not develop immunity against the parasite, falling ill whenever they are exposed to the parasite. The understanding of why immunity is not developed in the usual way against Plasmodium is crucial to the improvement of treatment and prevention. In this work, we study some aspects of the dynamics of the blood cycle of malaria using both modelling and data analysis of observed case-histories described by parasitemia time series. By comparing our simulations with experimental results we have shown that the different behaviour observed among patients may be associated to differences in the efficiency of the immune system to control the infection.


Malaria Cellular Automaton European Physical Journal Special Topic Good Simulation Nmer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© EDP Sciences/Società Italiana di Fisica/Springer-Verlag 2007

Authors and Affiliations

  • R.M. Zorzenon dos Santos
    • 1
  • S. T.R. Pinho
    • 2
  • C. P. Ferreira
    • 3
  • P. C.A. da Silva
    • 1
  1. 1.Departamento de FísicaUniversidade Federal de PernambucoRecifeBrazil
  2. 2.Departamento de FísicaUniversidade Federal da BahiaSalvadorBrazil
  3. 3.Departamento de BioestatísticaUniversidade Estadual de São PauloBotucatuBrazil

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