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Biomarkers of the psychophysiological state during the cognitive tasks estimated from the signals of the brain, cardiovascular and respiratory systems

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Abstract

Diagnostics of the psychophysiological state at rest and under stressful conditions is an important problem. We tested various biomarkers of the psychophysiological state of healthy volunteers at rest and while completing stress-inducing cognitive tasks, namely the Stroop color word test and mental arithmetic test. We tested the biomarkers based on the analysis of electroencephalograms, respiratory signals, and the signals of cardiovascular system. We investigated both the individual characteristics of these signals in the low-frequency range (less than 0.5 Hz), and characteristics of their interaction. According to our results, the most sensitive biomarkers of cognitive task stress are nonlinear phase coherence between the 0.15 and 0.40 Hz oscillations in the respiratory signal and heart rate variability, and integral power of the 0.15–0.40 Hz oscillations in the frontal lobe EEG leads.

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Data availability

The datasets generated during and analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

This research was supported from the Russian Federal Academic Leadership Program Priority 2030 at the Immanuel Kant Baltic Federal University.

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Authors and Affiliations

  1. Immanuel Kant Baltic Federal University, A. Nevskogo Street, 14, Kaliningrad, 236041, Russia

    Ekaterina I. Borovkova, Aleksey N. Hramkov, Vladimir I. Ponomarenko, Boris P. Bezruchko, Yurii M. Ishbulatov, Alexander V. Kurbako, Anatoly S. Karavaev & Mikhail D. Prokhorov

  2. Saratov State University, Astrakhanskaya Street, 83, Saratov, 410012, Russia

    Ekaterina I. Borovkova, Aleksey N. Hramkov, Elizaveta S. Dubinkina, Vladimir I. Ponomarenko, Boris P. Bezruchko, Yurii M. Ishbulatov, Alexander V. Kurbako, Anatoly S. Karavaev & Mikhail D. Prokhorov

  3. National Medical Research Center for Therapy and Preventive Medicine, Petroverigsky Per., 10, Moscow, 101000, Russia

    Ekaterina I. Borovkova

  4. Saratov Branch of Kotelnikov Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Zelyonaya Street, 38, Saratov, 410019, Russia

    Vladimir I. Ponomarenko, Boris P. Bezruchko, Alexander V. Kurbako, Anatoly S. Karavaev & Mikhail D. Prokhorov

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  1. Ekaterina I. Borovkova
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  2. Aleksey N. Hramkov
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  3. Elizaveta S. Dubinkina
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  4. Vladimir I. Ponomarenko
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  6. Yurii M. Ishbulatov
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  8. Anatoly S. Karavaev
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Correspondence to Ekaterina I. Borovkova or Aleksey N. Hramkov.

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Brain Physiology Meets Complex Systems. Guest editors: Thomas Penzel, Teemu Myllylä, Oxana V. Semyachkina-Glushkovskaya, Alexey Pavlov, Anatoly Karavaev.

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Borovkova, E.I., Hramkov, A.N., Dubinkina, E.S. et al. Biomarkers of the psychophysiological state during the cognitive tasks estimated from the signals of the brain, cardiovascular and respiratory systems. Eur. Phys. J. Spec. Top. 232, 625–633 (2023). https://doi.org/10.1140/epjs/s11734-022-00734-z

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