Abstract
A new proton therapy center is planned to be built in Rome, Italy. The project, named TOP-IMPLART, is developed by three institutions, ENEA (Agenzia Nazionale per le Nuove tecnologie, l’Energia e lo Sviluppo Economico Sostenibile - Italian national agency for new technologies, energy and sustainable economic development), ISS (Istituto Superiore di Sanità, Italian National Institute of Health) and IFO-IRE (Istituto Fisioterapico Ospedaliero - Istituto Regina Elena, Regina Elena, National Cancer Institute in Rome). The project is centered on a medium-energy proton accelerator designed as a sequence of linear accelerators. Two phases of construction are foreseen: the first (funded by the Italian Regione Lazio for 11 M€ spread over four years) with a maximum energy of 150 MeV and the second one up to 230 MeV. The segment up to 150 MeV is under construction and will be tested at the ENEA Research Center in Frascati before the transfer to IFO that is the clinical user. The basic concepts of the design are described here.
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References
L. Picardi, C. Ronsivalle, A. Vignati, Progetto del TOP Linac, ENEA Technical Report RT/INN/97/17 (in Italian) (1997).
L. Picardi, The TOP Project status, in Proceedings of the Particle Accelerator Conference 2001, Chicago, (2001), p.2491
ISS, Progetto Sviluppo dell’uso di protoni in terapia oncologica, Rapporti ISTISAN 04/40, edited by M. Belli, B. Caccia, M. Grandolfo, S. Onori, M.A. Tabocchini (2004), available on www.iss.it
L. Picardi, C. Ronsivalle, R. Hamm, Beam injection study of the TOP linac using an ACCSYS model PL-7 linac, in Proceedings EPAC2000, Vienna (2000) p. 1675
U. Amaldi et al., Rev. Accel. Sci. Technol. 2, 111 (2009).
L. Strigari, M. D’Andrea, A. Abate, M. Benassi, Phys. Med. Biol. 53, 5257 (2008).
The TERA Collaboration, The TERA Project and the Centre for Oncological Hadrontherapy, edited by U. Amaldi, M. Silari (INFN, Frascati, 1995).
The TERA Collaboration, The RITA Network and the Design of Compact Proton Accelerators, edited by U. Amaldi, M. Grandolfo, L. Picardi (INFN, 1996).
Patent N. RM95-A000564, 9/9/
L. Picardi, G. Orlandi, C. Ronsivalle, A. Vignati, THE TOP - ISS linear accelerator: a high frequency proton linac for therapy, in Proceedings of the European Particle Accelerator Conference 1996, Barcelona, (JACoW) THP049G
L. Picardi, C. Ronsivalle, A. Vignati, Measurement of cavities of the side coupled drift tube linac (SCDTL), in Proceedings of EPAC96, TH002A (1996).
L. Picardi, C. Ronsivalle, B. Spataro, Nucl. Instrum. Methods Phys. Res. A 425, 8 (1999).
L. Picardi, C. Ronsivalle, B. Spataro, Nucl. Instrum. Methods Phys. Res. B 170, 219 (2000).
L. Picardi, C. Ronsivalle, B. Spataro, Eur. Phys. J. Appl. Phys. 20, 61 (2002).
U. Amaldi, LIBO: a $3$GHz proton linac booster of $200$MeV for cancer treatment, in Proceedings of the XIX International Linear Accelerator Conference, Chicago, (1998), p. 633
P. Berra, Study, construction and test of a $3$GHz proton linac booster (LIBO) for cancer therapy, in Proceedings of EPAC2000, Vienna, Austria (2000) p. 2495
B. Szeless, Successful high power test of a proton linac booster (LIBO) prototype for hadrontherapy, in Proceedings of the Particle Accelerator Conference 2001, Chicago (2001), p. 642
V.G. Vaccaro, ACLIP: a $3$GHz side coupled linac to be used as a booster for $30$MeV Cyclotrons, Proc. Cycl. (2007) pp. 172-174
V.G. Vaccaro, Design, construction and low power RF tests of the first module of the ACLIP linac, in Proceedings of EPAC08, Genova (2008), pp. 1836-1838
V.G. Vaccaro, RF high power tests on the first module of the ACLIP linac, in Proceedings of PAC09, 4-8 May, Vancouver, Canada (2009) p. 4950
L. Picardi, C. Ronsivalle, B. Spataro, The first module of the $3$GHz Side Coupled Drift Tube Linac (SCDTL): numerical studies of RF properties and cold tests results, in Proceedings of EPAC2000, p. 1999
L. Picardi, High power RF tests of the first module of the TOP linac SCDTL structure, in Proceedings of EPAC 2006, Edinburgh, Scotland, p. 2313
Aster Capital Europe (HQ), 7 rue de Caumartin, 75009 Paris, France
L. Picardi, Accelerating a cyclotron $18$MeV proton beam by a SCDTL linac, in Proceedings PAC09, Vancouver, BC, Canada (JACoW, 2009) FR5REP096
K. Crandall, DESIGN and LINAC codes, private communication (1994).
D. Castelluccio, A novel realtime beam monitoring system in proton therapy treatments, Thesis, Rome, 2010. Available at http://www.iss.infn.it/webg3/pub/tesi/
S. Devicienti, L. Strigari, M. D’Andrea, M. Benassi, V. Dimiccoli, M. Portaluri, J. Exp. Clin. Cancer Res. 13, 29 (2010).
G.A.P. Cirrone, G. Cuttone, F. Di Rosa, L. Raffaele, G. Russo, S. Guatelli, Nucl. Phys. B 54, 150 (2006).
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Ronsivalle, C., Carpanese, M., Marino, C. et al. The TOP-IMPLART project. Eur. Phys. J. Plus 126, 68 (2011). https://doi.org/10.1140/epjp/i2011-11068-x
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DOI: https://doi.org/10.1140/epjp/i2011-11068-x