Advertisement

Theoretical study of actin layers attachment and separation

  • Sophie MarbachEmail author
  • Amélie Luise Godeau
  • Daniel Riveline
  • Jean-François Joanny
  • Jacques Prost
Regular Article

Abstract.

We use the theory of active gels to study theoretically the merging and separation of two actin dense layers akin to cortical layers of animal cells. The layers bind at a distance equal to twice the thickness of a free layer, thus forming a single dense layer, similar in this sense to a lamellipodium. When that unique layer is stretched apart, it is resilient to break apart up to a critical length larger than twice the thickness of a free layer. We show that this behavior can result from the high contractile properties of the actomyosin gel due to the activity of myosin molecular motors. Furthermore, we establish that the stability of the stretched single layer is highly dependent on the properties of the gel. Indeed, the nematic order of the actin filaments along the polymerizing membranes is a destabilizing factor.

Graphical abstract

Keywords

Living systems: Cellular Processes 

References

  1. 1.
    V.C. Abraham, V. Krishnamurthi, D.L. Taylor, F. Lanni, Biophys. J. 77, 1721 (1999)CrossRefGoogle Scholar
  2. 2.
    T.D. Pollard, G.G. Borisy, Cell 112, 453 (2003)CrossRefGoogle Scholar
  3. 3.
    J. Wu, I.A. Kent, N. Shekhar, T.J. Chancellor, A. Mendonca, R.B. Dickinson, T.P. Lele, Biophys. J. 106, 7 (2014)CrossRefADSGoogle Scholar
  4. 4.
    V. Achard, J.-L. Martiel, A. Michelot, C. Guérin, A.-C. Reymann, L. Blanchoin, R. Boujemaa-Paterski, Curr. Biol. 20, 423 (2010)CrossRefGoogle Scholar
  5. 5.
    J.-F. Joanny, K. Kruse, J. Prost, S. Ramaswamy, Eur. Phys. J. E 36, 52 (2013)CrossRefGoogle Scholar
  6. 6.
    H. Turlier, B. Audoly, J. Prost, J.-F. Joanny, Biophys. J. 106, 114 (2014)CrossRefADSGoogle Scholar
  7. 7.
    T.D. Pollard, L. Blanchoin, R.D. Mullins, Annu. Rev. Biophys. Biomol. Struct. 29, 545 (2000)CrossRefGoogle Scholar
  8. 8.
    O. Medalia, I. Weber, A.S. Frangakis, D. Nicastro, G. Gerisch, W. Baumeister, Science 298, 1209 (2002)CrossRefADSGoogle Scholar
  9. 9.
    G. Salbreux, G. Charras, E. Paluch, Trends Cell Biol. 22, 10 (2012)CrossRefGoogle Scholar
  10. 10.
    P.M. Bendix, G.H. Koenderink, D. Cuvelier, Z. Dogic, B.N. Koeleman, W.M. Brieher, C.M. Field, L. Mahadevan, D.A. Weitz, Biophys. J. 94, 3126 (2008)CrossRefADSGoogle Scholar
  11. 11.
    K. Kruse, J.-F. Joanny, F. Jülicher, J. Prost, K. Sekimoto, Eur. Phys. J. E 16, 5 (2005)CrossRefGoogle Scholar
  12. 12.
    J.-F. Joanny, F. Jülicher, K. Kruse, J. Prost, New J. Phys. 9, 422 (2007)CrossRefADSGoogle Scholar
  13. 13.
    A.C. Callan-Jones, F. Jülicher, New J. Phys. 13, 093027 (2011)CrossRefADSGoogle Scholar
  14. 14.
    R. Voituriez, J.F. Joanny, J. Prost, Europhys. Lett. 70, 404 (2005)CrossRefADSGoogle Scholar
  15. 15.
    S. Fürthauer, M. Neef, S.W. Grill, K. Kruse, F. Jülicher, New J. Phys. 14, 023001 (2012)CrossRefGoogle Scholar
  16. 16.
    S. Günther, K. Kruse, New J. Phys. 9, 417 (2007)CrossRefGoogle Scholar
  17. 17.
    G. Salbreux, J. Prost, J.F. Joanny, Phys. Rev. Lett. 103, 058102 (2009)CrossRefADSGoogle Scholar
  18. 18.
    K. Kruse, J.-F. Joanny, F. Jülicher, J. Prost, Phys. Biol. 3, 130 (2006)CrossRefADSGoogle Scholar
  19. 19.
    D.A. Lauffenburger, A.F. Horwitz, Cell 84, 359 (1996)CrossRefGoogle Scholar
  20. 20.
    I. Nedeva, G. Koripelly, D. Caballero, L. Chièze, B. Guichard, B. Romain, E. Pencreach, J.-M. Lehn, M.-F. Carlier, D. Riveline, Nat. Commun. 4, 2165 (2013)CrossRefADSGoogle Scholar
  21. 21.
    S. Diez, G. Gerisch, K. Anderson, A. Müller-Taubenberger, T. Bretschneider, Proc. Natl. Acad. Sci. U.S.A. 102, 7601 (2005)CrossRefADSGoogle Scholar
  22. 22.
    N. Watanabe, T.J. Mitchison, Science 295, 1083 (2002)CrossRefADSGoogle Scholar
  23. 23.
    F. Gerbal, P. Chaikin, Y. Rabin, J. Prost, Biophys. J. 79, 2259 (2000)CrossRefGoogle Scholar
  24. 24.
    V. Noireaux, R.M. Golsteyn, E. Friederich, J. Prost, C. Antony, D. Louvard, C. Sykes, Biophys. J. 78, 1643 (2000)CrossRefGoogle Scholar
  25. 25.
    F. Jülicher, K. Kruse, J. Prost, J.-F. Joanny, Phys. Rep. 449, 3 (2007)MathSciNetCrossRefADSGoogle Scholar
  26. 26.
    T. Kim, M.L. Gardel, E. Munro, Biophys. J. 106, 526 (2014)CrossRefADSGoogle Scholar

Copyright information

© EDP Sciences, SIF, Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Sophie Marbach
    • 1
    • 2
    Email author
  • Amélie Luise Godeau
    • 4
    • 5
  • Daniel Riveline
    • 4
    • 5
  • Jean-François Joanny
    • 1
    • 3
  • Jacques Prost
    • 1
  1. 1.Physico-Chimie Curie(Institut Curie, Cnrs UMR 168, UPMC), Institut Curie Centre de RechercheParisFrance
  2. 2.ICFP, Physics DepartmentEcole Normale Supérieure de ParisParisFrance
  3. 3.ESPCIParisFrance
  4. 4.Laboratory of Cell Physics, Institut de Science et d’Ingénierie Supramoléculaires, Institut de Génétique et de Biologie Moléculaire et CellulaireUniversité de Strasbourg and Centre National de la Recherche Scientifique UMR 7006StrasbourgFrance
  5. 5.Development and Stem Cells Program, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale (U964)Université de StrasbourgIllkirchFrance

Personalised recommendations