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Cell survival probability in a spread-out Bragg peak for novel treatment planning

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Abstract

The problem of variable cell survival probability along the spread-out Bragg peak is one of the long standing problems in planning and optimisation of ion-beam therapy. This problem is considered using the multiscale approach to the physics of ion-beam therapy. The physical reasons for this problem are analysed and understood on a quantitative level. A recipe of solution to this problem is suggested using this approach. This recipe can be used in the design of a novel treatment planning and optimisation based on fundamental science.

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Author information

Authors and Affiliations

  1. Department of Physics, Oakland University, Rochester, Michigan, 48309, USA

    Eugene Surdutovich

  2. MBN Research Center, 60438, Frankfurt am Main, Germany

    Eugene Surdutovich & Andrey V. Solov’yov

Authors
  1. Eugene Surdutovich
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  2. Andrey V. Solov’yov
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Corresponding author

Correspondence to Eugene Surdutovich.

Additional information

Contribution to the Topical Issue “Dynamics of Systems at the Nanoscale”, edited by Andrey Solov’yov and Andrei Korol.

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Surdutovich, E., Solov’yov, A.V. Cell survival probability in a spread-out Bragg peak for novel treatment planning. Eur. Phys. J. D 71, 210 (2017). https://doi.org/10.1140/epjd/e2017-80120-0

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  • DOI: https://doi.org/10.1140/epjd/e2017-80120-0

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