Advertisement

The European Physical Journal Special Topics

, Volume 222, Issue 10, pp 2687–2696 | Cite as

Synchronization of low-frequency oscillations in the cardiovascular system: Application to medical diagnostics and treatment

  • V.I. PonomarenkoEmail author
  • M.D. Prokhorov
  • A.S. Karavaev
  • A.R. Kiselev
  • V.I. Gridnev
  • B.P. Bezruchko
Regular Article Applications in Biology and Medicine

Abstract

We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1 Hz. A quantitative estimation of this synchronization based on calculation of relative time of phase synchronization of oscillations is proposed. We show that assessment of synchronization between the considered oscillations can be useful for selecting an optimal dose of beta-blocker treatment in patients after acute myocardial infarction. It is found out that low value of synchronization between the low-frequency rhythms in heart rate and blood pressure at the first week after acute myocardial infarction is a sensitive marker of high risk of mortality during the subsequent 5 years.

Keywords

Heart Rate Variability Acute Myocardial Infarction European Physical Journal Special Topic Acute Heart Failure Phase Synchronization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    S. Malpas, Am. J. Physiol. Heart Circ. Physiol. 282, H6 (2002)Google Scholar
  2. 2.
    M.A. Cohen, J.A. Taylor, J. Physiol. (London) 542, 669 (2002)ADSCrossRefGoogle Scholar
  3. 3.
    G. Parati, G. Mancia, M.D . Rienzo, P. Castiglioni, J.A. Taylor, P. Studinger, J. Appl. Physiol. 101, 676 (2006)CrossRefGoogle Scholar
  4. 4.
    A. Malliani, C. Julien, G.E. Billman, S. Cerutti, M.F. Piepoli, L. Bernardi, P. Sleight, M.A. Cohen, C.O. Tan, D. Laude, M. Elstad, K. Toska, PJ.M. Evans, D.L. Eckberg, J. Appl. Physiol. 101, 684 (2006)CrossRefGoogle Scholar
  5. 5.
    R.W. DeBoer, J.W. Karemaker, J. Stracke, Am. J. Physiol. Heart Circ. Physiol. 253, H680 (1987)Google Scholar
  6. 6.
    L. Bernardi, S. Leuzzi, A. Radaelli, C. Passino, J.A. Johnston, P. Sleight, Clin. Sci. 87, 649 (1994)Google Scholar
  7. 7.
    N. Montano, T. Gnecchi-Ruscone, A. Porta, F. Lombardi, A. Malliani, S.M. Barman, J. Auton. Nerv. Syst. 57, 116 (1996)CrossRefGoogle Scholar
  8. 8.
    R.L. Cooley, N. Montano, C. Cogliati, P. van de Borne, W. Richenbacher, R. Oren, V.K. Somers, Circulation 98, 556 (1998)CrossRefGoogle Scholar
  9. 9.
    M.D. Prokhorov, V.I. Ponomarenko, V.I. Gridnev, M.B. Bodrov, A.B. Bespyatov, Phys. Rev. E 68, 041913 (2003)ADSCrossRefGoogle Scholar
  10. 10.
    V.I. Ponomarenko, M.D. Prokhorov, A.B. Bespyatov, M.B. Bodrov, V.I. Gridnev, Chaos, Solitons Fractals 23, 1429 (2005)ADSzbMATHGoogle Scholar
  11. 11.
    A.S. Karavaev, M.D. Prokhorov, V.I. Ponomarenko, A.R. Kiselev, V.I. Gridnev, E.I. Ruban, B.P. Bezruchko, Chaos 19, 033112 (2009)ADSCrossRefGoogle Scholar
  12. 12.
    J.A. Taylor, D.L. Eckberg, Circulation 93, 1527 (1996)CrossRefGoogle Scholar
  13. 13.
    R. Bartsch, J.W. Kantelhardt, T. Penzel, S. Havlin, Phys. Rev. Lett. 98, 054102 (2007)ADSCrossRefGoogle Scholar
  14. 14.
    J. Halámek, T. Kára, P. Jurák, M. Souček, D.P. Francis, L.C. Davies, W.K. Shen, A.J.S. Coats, M. Novák, Z. Nováková, R. Panovský, J. Toman, J. Šumbera, V.K. Somers, Circulation 108, 292 (2003)CrossRefGoogle Scholar
  15. 15.
    Expert consensus document on β-adrenergic receptor blockers. The Task Force on Beta-Blockers of the European Society of Cardiology, Eur. Heart J. 25, 1341 (2004)Google Scholar
  16. 16.
    Expert consensus document on Universal definition of myocardial infarction. Task Force for the Redefinition of Myocardial Infarction, Eur. Heart J. 28, 2525 (2007)Google Scholar

Copyright information

© EDP Sciences and Springer 2013

Authors and Affiliations

  • V.I. Ponomarenko
    • 1
    • 2
    Email author
  • M.D. Prokhorov
    • 1
  • A.S. Karavaev
    • 1
    • 2
  • A.R. Kiselev
    • 3
  • V.I. Gridnev
    • 3
  • B.P. Bezruchko
    • 1
    • 2
  1. 1.Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of SciencesSaratovRussia
  2. 2.Department of Nano- and Biomedical TechnologiesSaratov State UniversitySaratovRussia
  3. 3.Saratov Research Institute of CardiologySaratovRussia

Personalised recommendations