The European Physical Journal Special Topics

, Volume 157, Issue 1, pp 61–77

Beyond the Keller-Segel model

Microscopic modelling of bacterial colonies
  • P. Romanczuk
  • U. Erdmann
  • H. Engel
  • L. Schimansky-Geier
Article

Abstract.

Complex spatio-temporal patterns of cell clusters were observed in colonies of chemotactic bacteria such as Escherichia coli or Sallmonella typhimurium. The production of a potent chemoattractant by the bacteria themselves as a reaction to certain nutrients is the essential factor for this pattern formation. Additional collective dynamics, such as collective translation and rotation of bacterial clusters were reported from experiments on bacterial colonies. Motivated by this observations we suggest a simple model for the description of bacterial colonies using the concept of active Brownian particles. Individual based models represent an interesting alternative to the usually employed mean field chemotaxis-diffusion equations (Keller-Segel model) as they allow us to study the macroscopic pattern formation of the colony, the collective dynamics of bacterial ensembles, as well as the microscopic dynamics of individual cells. In this paper we derive microscopic model equations from basic assumptions about bacterial dynamics, discuss the parameter choice by comparison with biological data and analyse the macroscopic and microscopic dynamics of the system. Finally we extend the model by a velocity-alignment (swarming) interaction which leads to novel collective dynamics in the system.

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Copyright information

© EDP Sciences/Società Italiana di Fisica/Springer-Verlag 2008

Authors and Affiliations

  • P. Romanczuk
    • 1
  • U. Erdmann
    • 2
  • H. Engel
    • 3
  • L. Schimansky-Geier
    • 1
  1. 1.Institute of Physics, Humboldt University BerlinBerlinGermany
  2. 2.Helmholtz Association, Anna-Louisa-Karsch-Str. 2BerlinGermany
  3. 3.Institute of Theoretical Physics, Technical University BerlinBerlinGermany

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