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Bilayer properties of giant magnetic liposomes formed by cationic pyridine amphiphile and probed by active deformation under magnetic forces

  • O. Petrichenko
  • K. Ērglis
  • A. Cēbers
  • A. Plotniece
  • K. Pajuste
  • G. Béalle
  • Ch. Ménager
  • E. Dubois
  • R. Perzynski
Regular Article

Abstract.

We synthesize giant magnetic liposomes by a reverse-phase evaporation method (REV) using a new self-assembling Cationic Pyridine Amphiphile (CPA) derived from 1,4-dihydropyridine as liposome-forming agent and a magnetic ferrofluid based on \( \gamma\) - Fe 2 O 3 nanoparticles. Having in view the potential interest of CPA in targeted transport by magnetic forces, the mechanical elastic properties of such bilayers are here directly investigated in vesicles loaded with magnetic nanoparticles. Bending elastic modulus K b ∼ 0.2 to 5k B T and pre-stress \( \tau_{0}\) ∼ 3.2 to 12 . 10-6 erg/cm 2 are deduced from the under-field deformations of the giant magnetic liposomes. The obtained Kb values are discussed in terms of A. Wurgers's theory.

Graphical abstract

Keywords

Soft Matter: Colloids and Nanoparticles 

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Copyright information

© EDP Sciences, SIF, Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • O. Petrichenko
    • 1
  • K. Ērglis
    • 1
  • A. Cēbers
    • 1
  • A. Plotniece
    • 2
  • K. Pajuste
    • 2
  • G. Béalle
    • 3
  • Ch. Ménager
    • 3
  • E. Dubois
    • 3
  • R. Perzynski
    • 3
  1. 1.University of LatviaRıgaLatvia
  2. 2.Institute of Organic SynthesisRıgaLatvia
  3. 3.UPMC University Paris 6 - PECSA UMR CNRS 7195ParisFrance

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