Efficient calculation of local dose distributions for response modeling in proton and heavier ion beams

  • Steffen Greilich
  • Ute Hahn
  • Markus Kiderlen
  • Claus E. Andersen
  • Niels Bassler
Regular Article
Part of the following topical collections:
  1. Topical Issue: Nano-scale Insights into Ion-beam Cancer Therapy


We present an algorithm for fast and accurate computation of the local dose distribution in MeV beams of protons, carbon ions or other heavy charged particles. It uses compound Poisson modeling of track interaction and successive convolutions for fast computation. It can handle arbitrary complex mixed particle fields over a wide range of fluences. Since the local dose distribution is the essential part of several approaches to model detector efficiency and cellular response it has potential use in ion-beam dosimetry, radiotherapy, and radiobiology.


Dose Distribution Linear Energy Transfer Single Track Local Dose Heavy Charged Particle 
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Copyright information

© EDP Sciences, SIF, Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Steffen Greilich
    • 1
  • Ute Hahn
    • 2
  • Markus Kiderlen
    • 2
  • Claus E. Andersen
    • 3
  • Niels Bassler
    • 4
  1. 1.Division of Medical Physics in Radiation OncologyGerman Cancer Research Center (DKFZ)HeidelbergGermany
  2. 2.Department of MathematicsAarhus UniversityAarhus CDenmark
  3. 3.Center for Nuclear TechnologiesTechnical University of DenmarkRoskildeDenmark
  4. 4.Department of Physics and AstronomyAarhus UniversityAarhus CDenmark

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