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Positive and negative ion formation via slow electron collisions with 5-bromouridine

  • S. Denifl
  • P. Candori
  • S. Ptasińska
  • P. Limão-Vieira
  • V. Grill
  • T. D. Märk
  • P. ScheierEmail author
Processes in Biomolecules

Abstract.

Cation and anion formation is studied experimentally upon inelastic low energy electron interactions with 5-bromouridine (BrUrd) using a crossed electron/neutral beams set-up combined with a quadrupole mass spectrometer. The BrUrd molecule belongs to the class of radiosensitizers that increase the sensitivity of DNA (or RNA) to ionizing radiation. In the case of positive ion formation the ionization efficiency curves are measured near the threshold and the corresponding appearance energies are determined using a non-linear least square fitting procedure. The anion yields are investigated in the electron energy range from about 0 to 14 eV. From the comparison of the present results for negative and positive ions information concerning the underlying mechanism of radiosensitizers is deduced.

Keywords

Anion Formation Quadrupole Mass Spectrometer Electron Interaction Ionization Efficiency Anion Yield 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© EDP Sciences/Società Italiana di Fisica/Springer-Verlag 2005

Authors and Affiliations

  • S. Denifl
    • 1
  • P. Candori
    • 1
  • S. Ptasińska
    • 1
  • P. Limão-Vieira
    • 1
  • V. Grill
    • 1
  • T. D. Märk
    • 1
  • P. Scheier
    • 1
    Email author
  1. 1.Institut für Ionenphysik, Center for Molecular Biosciences, Leopold Franzens UniversitätInnsbruckAustria

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