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Eco-friendly, Water Mediated, One-Pot Synthesis of 2-(5,6-Dicyano-1H-benzo[d]imidazol-2-yl)-N-arylbenzamides and Their Antifungal Activity Testing

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Abstract

Ecofriendly, water mediated, one-pot three-component synthesis of novel 2-(5,6-dicyano-1H-benzo[d]imidazol-2-yl)-N-arylbenzamides have been developed by the reactions of phthalic anhydride with substituted anilines and 4,5-diaminophthalonitrile in water for 90–120 min at 100°C without any catalyst. The reactions involve easy workup, provide excellent yields, and use water as a green solvent.

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Authors and Affiliations

  1. Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad, 500085, Hyderabad, India

    B. S. Narayana, Y. D. Reddy & Ch. V. R. Reddy

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  1. B. S. Narayana
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  2. Y. D. Reddy
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  3. Ch. V. R. Reddy
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Correspondence to Ch. V. R. Reddy.

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Narayana, B.S., Reddy, Y.D. & Reddy, C.V.R. Eco-friendly, Water Mediated, One-Pot Synthesis of 2-(5,6-Dicyano-1H-benzo[d]imidazol-2-yl)-N-arylbenzamides and Their Antifungal Activity Testing. Russ J Org Chem 59, 305–311 (2023). https://doi.org/10.1134/S1070428023020124

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