Advances in Gerontology

, Volume 5, Issue 2, pp 128–131 | Cite as

Influence of millimeter-wave electromagnetic radiation on nitric oxide synthesis with aging of vessel endothelium in vitro

  • I. D. Molodzova
  • D. S. Medvedev
  • V. O. Polyakova
  • N. S. LinkovaEmail author
  • G. I. Gurko


Millimeter-wave electromagnetic radiation (EHF-therapy) is an effective method for treating various age-related pathologies, including cardiovascular diseases. Multidirectional changes in the synthesis of NO-synthase (eNOS) and endothelin-1 and the expression of angiotensin-2 and vasopressin were observed during EHF irradiation of aging human endothelial cell cultures, depending on the duration of the irradiation. These data showed that the EHF irradiation stimulates the functional activity of endotheliocytes, which could be of importance in the search for new approaches to the treatment of arterial hypertension and atherosclerosis.


EHF radiation vessel endothelium nitric oxide aging 


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Copyright information

© Pleiades Publishing, Ltd. 2015

Authors and Affiliations

  • I. D. Molodzova
    • 1
  • D. S. Medvedev
    • 1
  • V. O. Polyakova
    • 1
    • 2
  • N. S. Linkova
    • 1
    • 3
    Email author
  • G. I. Gurko
    • 1
  1. 1.St. Petersburg Institute of Bioregulation and GerontologySt. PetersburgRussia
  2. 2.Ott Research Institute of Obstetrics and GynecologyRussian Academy of Medical SciencesSt. PetersburgRussia
  3. 3.St. Petersburg State Polytechnical UniversitySt. PetersburgRussia

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