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Morphological and mechanical peculiarities of erythrocytes and neutrophils from patients of different age groups with chronic obstructive pulmonary disease and bronchial asthma

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Abstract

Current electron microscopy methods permit the study of peculiarities of cellular response in chronic obstructive pulmonary disease and bronchial asthma, as well as diagnosis of the severity of the diseases, which is especially important in the senile-aged.

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References

  1. Berezyuk, L.V., Clinical and biochemical criteria of inflammation and hypoxia in chronic obstructive pulmonary disease, Cand. Sci. (Med.) Dissertation, Chelyabinsk, 2006.

    Google Scholar 

  2. Galaktionova, L.P., Peculiarities of the oxidant-antioxidant status of patients with bronchial asthma after drug and non-drug correction, Doctoral Sci. (Biol.) Dissertation, Barnaul, 2004.

    Google Scholar 

  3. Zabinyakov, N.A., Assessment of surface and mechanical properties of erythrocytes and neutrophils at acute hypoxia by atomic force microscopy, Mater. XXIV Ross. konf. po elektronnoi mikroskopii “RKEM-2012” (Proc. XXIV Russ. Conf. on Electron Microscopy “RKEM-2012”), Chernogolovka, 2012.

    Google Scholar 

  4. Lebedev, D.V., Chuklanov, A.P., Bukharaev, A.A., and Druzhinina, O.S., Measuring young’s modulus of biological objects in a liquid medium using an atomic force microscope with a special probe, Tech. Phys. Lett., 2009, vol. 35, no. 4, pp. 371–374.

    Article  CAS  Google Scholar 

  5. Markin, A.V., Respiratory support at acute bronchial failure in patients with severe pneumonia and exacerbation of chronic obstructive pulmonary disease, Cand. Sci. (Biol.) Dissertation, Barnaul, 2004.

    Google Scholar 

  6. Popova, I.E., Study of structural properties of the blood erythrocytes of newborns with oxidative stress caused by hypoxia, Cand. Sci. (Biol.) Dissertation, Voronezh, 2007.

    Google Scholar 

  7. Skorkina, M.Yu., Fedorova, M.Z., Sladkova, E.A., and Zabinyakov, N.A., Elastic properties of blood cells of patients with leukemia, in Mater. III Evraziiskogo kongressa po meditsinskoi fizike i inzhenerii “Meditsinskaya fizika-2010” (Proc. III Eurasian Congress on Medical Physics and Engineering “Medical Physics-2010”), Moscow, 2010, vol. 1, pp. 349–352.

    Google Scholar 

  8. Kharitonenko, E.Yu., The clinical course of chronic obstructive pulmonary disease in elderly patients—the veterans of the Great Patriotic war. Assessment of functional status and life quality, Cand. Sci. (Med.) Dissertation, St. Petersburg, 2008.

    Google Scholar 

  9. Shmelev, E.I., Differences in the diagnosis and treatment of bronchial asthma and chronic obstructive pulmonary disease, Consilium Medicum, 2002, no. 4, pp. 492–496.

    Google Scholar 

  10. Eticheskaya ekspertiza biomeditsinskikh issledovanii: Prakticheskie rekomendatsii (Ethical Assessment of Biomedical Studies: Practical Recommendations), Belousov, Yu.B., Ed., Moscow: Ross. O-vo Klin. Issled., 2005.

    Google Scholar 

  11. Baskurt, O.K., Gelmont, D., and Meiselman, H.J., Red blood cell deformability in sepsis, Am. J. Respir. Crit. Care Med., 1998, vol. 57, no. 2, pp. 421–427.

    Article  Google Scholar 

  12. Boulay, M.E. and Boulet, L.P., Lower airway inflammatory responses to repeated very low-dose allergen challenge in allergic rhinitis and asthma, Clin. Exp. Allergy, 2002, vol. 32, pp. 1441–1447.

    Article  PubMed  Google Scholar 

  13. Global Initiative for Asthma (GINA), Global Strategy for Asthma Management and Prevention, Vancouver, Canada. Revised February 23, 2012.

    Google Scholar 

  14. Global Initiative for Chronic Obstructive Lung Disease (GOLD), Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease, Manchester, UK. Revised February 21, 2011.

    Google Scholar 

  15. Piagnerelli, M., Boudjeltia, K. Z., Rapotec, A., et al., Neuraminidase alters red blood cells in sepsis, Am. J. Respir. Crit. Care Med., 2009, vol. 37, no. 4, pp. 1244–1250.

    Article  CAS  Google Scholar 

  16. Pic, K.R., Brechtefeld, D., and Walzog, B., Intraluminal crawling versus interstitial neutrophil migration during inflammation, Mol. Immunol., 2013. Online pub.

    Google Scholar 

  17. Roche, N. and Huchon, G., Epidemiology of chronic obstructive pulmonary disease, Rev. Prat., 2004, vol. 54, no. 13, pp. 1408–1413.

    PubMed  Google Scholar 

  18. Wagner, J.G. and Roth, R.A., Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature, Pharmacol. Rev., 2000, vol. 52, no. 3, pp. 349–374.

    PubMed  CAS  Google Scholar 

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Correspondence to K. I. Proshchayeu.

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Original Russian Text © N.A. Zabinyakov, K.I. Proshchayeu, P.G. Dovgii, A.N. Poltoratskii, G.A. Ryzhak, 2013, published in Uspekhi Gerontologii, 2013, Vol. 26, No. 2, pp. 373–378.

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Zabinyakov, N.A., Proshchayeu, K.I., Dovgii, P.G. et al. Morphological and mechanical peculiarities of erythrocytes and neutrophils from patients of different age groups with chronic obstructive pulmonary disease and bronchial asthma. Adv Gerontol 4, 78–82 (2014). https://doi.org/10.1134/S2079057014010147

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