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A new class of RNAs and the centrosomal hypothesis of cell aging

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Abstract

The recent discovery of a new class of RNAs, which are called centrosomal RNAs, in the centrosome is indirect proof of the centrosome hypothesis of cell differentiation and aging, in our opinion. The presence of a reverse transcriptase domain in RNAs of this class and the high specificity of this RNA for the organoid may make the centrosome a site for information storage and reproduction. The ability of this organelle to fulfill these functions is one of the basic postulates of the centrosome hypothesis of cell differentiation and aging.

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Authors and Affiliations

  1. Beritashvili Center for Experimental Biomedicine, Gotua str. 14, Tbilisi, 0160, Georgia

    K. Chichinadze

  2. I. Javakhishvili Tbilisi State University, Chavchavadze ave. 5, Tbilisi, 0160, Georgia

    K. Chichinadze

  3. Systemic Research Center, Vaja-Pshavela ave. 18A, Tbilisi, 0160, Georgia

    J. Tkemaladze & A. Lazarashvili

Authors
  1. K. Chichinadze
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  2. J. Tkemaladze
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  3. A. Lazarashvili
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Correspondence to K. Chichinadze.

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Original Russian Text © K. Chichinadze, J. Tkemaladze, A. Lazarashvili, 2012, published in Uspekhi Gerontologii, 2012, Vol. 25, No. 1, pp. 23–28.

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Chichinadze, K., Tkemaladze, J. & Lazarashvili, A. A new class of RNAs and the centrosomal hypothesis of cell aging. Adv Gerontol 2, 287–291 (2012). https://doi.org/10.1134/S2079057012040054

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