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Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects


Materials for 3D printing of porous composite materials (CM) that are based on sodium alginate–tricalcium phosphate are developed. Physicochemical and biological studies of CM in vitro are performed using a model of two adherent cells lines, immortalized human fibroblasts (HF, strain 1608h TERT) and human osteosarcoma (MG-63) that are cultivated up to 21 days. The cytocompatibility and matrix properties are studied by an MTT assay.

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Correspondence to V. S. Komlev.

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Original Russian Text © V.S. Komlev, N.S. Sergeeva, A.Yu. Fedotov, I.K. Sviridova, V.A. Kirsanova, S.A. Akhmedova, A.Yu. Teterina, Yu.V. Zobkov, E.A. Kuvshinova, Ya.D. Shanskiy, S.M. Barinov, 2016, published in Materialovedenie, 2016, No. 3, pp. 38–42.

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Komlev, V.S., Sergeeva, N.S., Fedotov, A.Y. et al. Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects. Inorg. Mater. Appl. Res. 7, 630–634 (2016).

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