Abstract
The surface of a VNIITU-1 carbon mesoporous hemosorbent is modified with poly-N-vinylpyrrolidone, which possesses its own antibacterial activity. The modification is performed in two steps: (1) impregnation of the monomer, N-vinylpyrrolidone, and the initiator in an aqueous solution and (2) polymerization in an inert atmosphere. The composition of products produced during polymerization reaction is analyzed by NMR 13C. The texture characteristics, the relief and the morphology, and the content of nitrogen in the initial and modified sorbents are studied by current physicochemical methods. Bench tests show that the contact with the modified sorbent leads to a decrease in the amount of Staphylococcus aureus bacterial cells and inhibition of their growth in comparison with the initial carbon sorbent.
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References
Surovikin, V.F., P’yanova, L.G., and Luzyanina, L.G., Ross. Khim. Zh., 2007, vol. L1, no. 5, p. 159.
Nikolaev, V.G. and Strelko, V.V., Gemosorbtsiya na aktivirovannykh uglyakh (Hemosorption on Activated Carbon), Kiev: Naukova Dumka, 1979.
Pyanova, L.G., Luzyanina, L.G., Drozdov, V.A., et al., Prot. Met. Phys. Chem. Surf., 2010, vol. 46, no. 3, p. 320.
Likholobov, V.A., P’yanova, L.G., Boronin, A.I., et al., Prot. Met. Phys. Chem. Surf., 2011, vol. 47, no. 2, p. 181.
Chernikova, E.V., Terpugov, P.S., Fillipov, A.N., et al., Russ. J. Appl. Chem., 2009, vol. 82, no. 10, p. 1882.
Afinogenov, G.E. and Panarin, E.F., Antimikrobnye polimery (Antimicrobial Polymers), St. Petersburg: Gippokrat, 1993.
Sidel’kovskaya, F.P., Khimiya N-vinilpirrolidona i ego polymerov (Chemistry of N-Vinylpyrrolidone and its Polymers, Moscow: Nauka, 1970.
Kirsh, Yu.E., Poli-N-vinilpirrolidon I drugie poli-N-vinilamidy (Poly-N-vinylpyrrolidone and other Poly-N-vinylamides, Moscow: Nauka, 1998.
Surovikin, V.F., Plaksin, G.V., Semicolenov, V.A., et al., RF Patent 1233767, 1992.
Surovikin, V.F., Luzyanina, L.S., P’yanova, L.G., et al., RF Patent 2211727, 2003.
Official methods of analysis of the Association of Official Analytical Chemists, Horwitz, W., Ed., Washington DC, 1970.
Grigor’ev, A.V., Zemskov, V.S., Shor-Chudnovskii, M.E., et al., Mikroflora, 1990, no. 3, p. 42.
Leikin, Yu.A., Cherkasova, T.A., Kumpanenko, I.V., et al., Ross. Khim. Zh., 2006, vol. L, no 5, p. 69.
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Original Russian Text © O.N. Baklanova, L.G. P’yanova, V.P. Talzi, O.A. Knyazheva, A.V. Sedanova, T.I. Dolgikh, V.A. Likholobov, 2012, published in Fizikokhimiya Poverkhnosti i Zashchita Materialov, 2012, Vol. 48, No. 4, pp. 363–369.
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Baklanova, O.N., P’yanova, L.G., Talzi, V.P. et al. Modification of carbon sorbent surface by poly-N-vinylpyrrolidone in application medicine. Prot Met Phys Chem Surf 48, 427–433 (2012). https://doi.org/10.1134/S2070205112040041
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DOI: https://doi.org/10.1134/S2070205112040041