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Effect of Roundup on the Activities of Glycosidase in the Intestines of Typical and Facultative Ichthyophages as a Function of Temperature and pH

  • ECOLOGICAL PHYSIOLOGY AND BIOCHEMISTRY OF HYDROBIONTS
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Abstract

In vitro studies of the effect of the herbicide Roundup (25 µg/L) on the activity of glycosidases that hydrolyze starch in the intestinal mucosa and chyme of typical (pike Esox lucius L., zander Sander lucioperca (L.), and wels catfish Silurus glanis L.) and facultative (common perch Perca fluviatilis L. and burbot Lota lota (L.)) ichthyophages have revealed the dependence of the strength and direction of its effect on the fish species, as well as on the localization of enzymes, temperature, and pH. The greatest inhibitory effect of Roundup on the glycosidase activity of intestinal mucosa and chyme was demonstrated at acidic pH levels. The decrease in temperature at neutral pH level, as a rule, eliminates the inhibitory effect of Roundup on the glycosidases of intestinal mucosa, although the inhibitory effect increases at acidic pH levels.

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Funding

This work was performed as part of State Assignment No. AAAA-A18-118012690102-9.

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Authors and Affiliations

  1. Yaroslavl State Medical University, Yaroslavl, Russia

    A. I. Aminov

  2. Papanin Institute for Biology of Inland Waters, Russian Academy of Sciences, Nekouzskii raion, Yaroslavl oblast, Borok, Russia

    I. L. Golovanova

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  1. A. I. Aminov
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  2. I. L. Golovanova
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Correspondence to I. L. Golovanova.

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Conflict of interest. The authors declare that they have no conflict of interest.

Statement on the welfare of animals. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

Additional information

Translated by T. Kuznetsova

Acronyms: AA, amylolytic activity; LC50, median lethal concentration for Roundup.

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Aminov, A.I., Golovanova, I.L. Effect of Roundup on the Activities of Glycosidase in the Intestines of Typical and Facultative Ichthyophages as a Function of Temperature and pH. Inland Water Biol 13, 291–296 (2020). https://doi.org/10.1134/S1995082920020029

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