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Nanoparticles Manifesting Antibacterial Effects: Properties, Production, Mechanism of Action, and Applications

  • NANOBIOMEDICINE AND NANOPHARMACEUTICALS
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Abstract

The emergence of new infectious diseases and the rapid development of drug resistance in pathogenic bacteria and fungi are a serious problem of modern medicine; therefore, a relevant issue is to develop novel methods of counteraction and detection of antimicrobial agents among natural and inorganic substances and the development of diagnostic, prophylactic, and therapeutic drugs. In the present work, we have considered gold, magnesium oxide, copper oxide, alumina, and zinc oxide nanoparticles that have proved to be potential antibacterial and antifungal agents, as well as the methods of their production, physicochemical properties, mechanisms of action, and applications. Examples of toxicity of nanoparticles for the following microorganisms are given: Proteus spp., Salmonella spp., Еscherichia coli, Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, etc. It is a promising trend to use these nanoparticles as antitumor agents and antifungal and antimicrobial drugs against pathogenic and drug-resistant microbes.

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Authors and Affiliations

  1. Federal State Institute of Health, Rostov-on-Don Plague Control Research Institute, Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare, Rostov-on-Don, Russia

    E. G. Matsakova & D. I. Simakova

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  1. E. G. Matsakova
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  2. D. I. Simakova
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Correspondence to E. G. Matsakova.

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Translated by E.V. Makeeva

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Matsakova, E.G., Simakova, D.I. Nanoparticles Manifesting Antibacterial Effects: Properties, Production, Mechanism of Action, and Applications. Nanotechnol Russia 15, 236–240 (2020). https://doi.org/10.1134/S1995078020020159

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